ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019428 Fkbp8 10090 + 8:70527724-70535328 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075491 Fkbp8-002 70527747-70535326 protein_coding
  ENSMUST00000119353 Fkbp8-001 70527724-70535328 protein_coding
  ENSMUST00000119425 Fkbp8-006 70528816-70529583 protein_coding
  ENSMUST00000119698 Fkbp8-003 70527846-70535327 protein_coding
  ENSMUST00000123052 Fkbp8-010 70531734-70534956 retained_intron
  ENSMUST00000125741 Fkbp8-007 70531124-70534171 retained_intron
  ENSMUST00000126613 Fkbp8-009 70532184-70534867 retained_intron
  ENSMUST00000128513 Fkbp8-005 70528009-70530598 retained_intron
  ENSMUST00000134299 Fkbp8-008 70532121-70534971 retained_intron
  ENSMUST00000134893 Fkbp8-011 70534117-70535057 nonsense_mediated_decay
  ENSMUST00000144766 Fkbp8-004 70527762-70532453 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000075491ENSMUST00000119353
Transcript ID C166 Tie2+ EC mES
ENSMUST00000075491 83.994±1.17 62.883±37.86 N/A
ENSMUST00000119353 N/A N/A 112.985±17.20

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IBA protein peptidyl-prolyl isomerization
GO:0001708 IMP cell fate specification
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0005528 IBA FK506 binding
GO:0005739 IDA mitochondrion
GO:0005740 IDA mitochondrial envelope
GO:0006915 IEA apoptotic process
GO:0007224 IGI smoothened signaling pathway
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010468 IGI regulation of gene expression
GO:0016020 IEA membrane
GO:0021904 IMP dorsal/ventral neural tube patterning
GO:0021915 IMP neural tube development
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030510 IGI regulation of BMP signaling pathway
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0035264 IGI multicellular organism growth
GO:0042802 IEA identical protein binding
GO:0043010 IMP camera-type eye development
GO:0043066 IMP negative regulation of apoptotic process
GO:0061077 IBA chaperone-mediated protein folding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001734 fkbp8 protein_coding Danio_rerio
ENSG00000105701 FKBP8 FK506 binding protein 8, 38kDa protein_coding Homo_sapiens

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