ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020458 Rtn4 10090 + 11:29692947-29744331 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060992 Rtn4-009 29718563-29742916 protein_coding
  ENSMUST00000078830 Rtn4-007 29692947-29744331 protein_coding
  ENSMUST00000102841 Rtn4-008 29693774-29742916 protein_coding
  ENSMUST00000102842 Rtn4-006 29692947-29742916 protein_coding
  ENSMUST00000102843 Rtn4-005 29692947-29742916 protein_coding
  ENSMUST00000125735 Rtn4-002 29736400-29742347 processed_transcript
  ENSMUST00000126162 Rtn4-001 29740998-29742285 processed_transcript
  ENSMUST00000141719 Rtn4-003 29733773-29742347 processed_transcript
  ENSMUST00000156217 Rtn4-004 29733698-29742435 processed_transcript
  ENSMUST00000170731 Rtn4-201 29692948-29742111 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000060992ENSMUST00000078830ENSMUST00000102841ENSMUST00000102842ENSMUST00000102843ENSMUST00000170731
Transcript ID C166 Tie2+ EC mES
ENSMUST00000060992 N/A 20.163±2.30 N/A
ENSMUST00000078830 N/A N/A 4.861±1.06
ENSMUST00000102841 13.562±3.36 10.369±2.81 N/A
ENSMUST00000102842 106.157±16.44 75.110±18.30 32.397±4.32
ENSMUST00000102843 16.395±4.08 4.776±0.00 10.022±2.63
ENSMUST00000170731 49.783±9.77 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005635 ISS nuclear envelope
GO:0005783 IDA endoplasmic reticulum
GO:0007399 IDA nervous system development
GO:0007413 IMP axonal fasciculation
GO:0016021 IEA integral component of membrane
GO:0021801 IMP cerebral cortex radial glia guided migration
GO:0030176 ISS integral component of endoplasmic reticulum membrane
GO:0030308 IEA negative regulation of cell growth
GO:0030334 IEA regulation of cell migration
GO:0030517 ISS negative regulation of axon extension
GO:0042995 IDA cell projection
GO:0043025 IDA neuronal cell body
GO:0044822 IEA poly(A) RNA binding
GO:0051960 IMP regulation of nervous system development
GO:0060317 IMP cardiac epithelial to mesenchymal transition
GO:0070062 IEA extracellular vesicular exosome
GO:0071786 IEA endoplasmic reticulum tubular network organization
GO:2000172 IMP regulation of branching morphogenesis of a nerve

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044601 rtn4a protein_coding Danio_rerio
ENSG00000115310 RTN4 reticulon 4 protein_coding Homo_sapiens

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