ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020826 Nos2 10090 + 11:78920787-78960254 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018610 Nos2-001 78920787-78960254 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000018610
Transcript ID C166 Tie2+ EC mES
ENSMUST00000018610 0.007±0.00 1.161±0.25 0.070±0.06

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007SM CIL_0007SM_0002 VISTA
CIL_0003LO CIL_0003LO_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 IDA nitric-oxide synthase activity
GO:0005102 IEA receptor binding
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005516 TAS calmodulin binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005777 IEA peroxisome
GO:0005829 TAS cytosol
GO:0006527 IDA arginine catabolic process
GO:0006801 IMP superoxide metabolic process
GO:0006809 IDA nitric oxide biosynthetic process
GO:0006954 TAS inflammatory response
GO:0007263 IBA nitric oxide mediated signal transduction
GO:0007623 IEP circadian rhythm
GO:0010181 IDA FMN binding
GO:0010629 IGI negative regulation of gene expression
GO:0018119 IDA peptidyl-cysteine S-nitrosylation
GO:0020037 IDA heme binding
GO:0030863 IDA cortical cytoskeleton
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0032496 IDA response to lipopolysaccharide
GO:0034617 IDA tetrahydrobiopterin binding
GO:0034618 IDA arginine binding
GO:0042127 IGI regulation of cell proliferation
GO:0042177 IDA negative regulation of protein catabolic process
GO:0042742 IMP defense response to bacterium
GO:0042803 IDA protein homodimerization activity
GO:0045776 IBA negative regulation of blood pressure
GO:0045909 IBA positive regulation of vasodilation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050660 IDA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0050796 IEA regulation of insulin secretion
GO:0051712 IEA positive regulation of killing of cells of other organism
GO:0055114 IEA oxidation-reduction process
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071346 IDA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026925 nos2a protein_coding Danio_rerio
ENSDARG00000031976 nos2b protein_coding Danio_rerio
ENSG00000007171 NOS2 nitric oxide synthase 2, inducible protein_coding Homo_sapiens

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