ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021055 Esr2 10090 - 12:76120419-76177259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076634 Esr2-201 76120439-76177259 protein_coding
  ENSMUST00000101291 Esr2-002 76120419-76177259 protein_coding
  ENSMUST00000110421 Esr2-001 76120419-76167715 protein_coding
  ENSMUST00000133564 Esr2-003 76120419-76177259 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000110421ENSMUST00000133564
Transcript ID C166 Tie2+ EC mES
ENSMUST00000110421 0.010±0.00 0.059±0.03 0.035±0.00
ENSMUST00000133564 0.006±0.00 0.207±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00010O CIL_00010O_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001046 IEA core promoter sequence-specific DNA binding
GO:0001541 IMP ovarian follicle development
GO:0001764 IMP neuron migration
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005496 ISS steroid binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007420 IMP brain development
GO:0008270 IEA zinc ion binding
GO:0008285 IGI negative regulation of cell proliferation
GO:0008628 IMP hormone-mediated apoptotic signaling pathway
GO:0019899 IEA enzyme binding
GO:0030284 IEA estrogen receptor activity
GO:0030520 IMP intracellular estrogen receptor signaling pathway
GO:0034056 IEA estrogen response element binding
GO:0042127 IMP regulation of cell proliferation
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060065 IGI uterus development
GO:0060068 IGI vagina development
GO:0060740 IMP prostate gland epithelium morphogenesis
GO:0060743 IMP epithelial cell maturation involved in prostate gland development
GO:0060766 IMP negative regulation of androgen receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016454 esr2a protein_coding Danio_rerio
ENSDARG00000034181 esr2b protein_coding Danio_rerio
ENSG00000140009 ESR2 estrogen receptor 2 (ER beta) protein_coding Homo_sapiens

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