ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024151 Msh2 10090 + 17:87672330-87723713 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024967 Msh2-001 87672330-87723713 protein_coding
  ENSMUST00000172596 Msh2-004 87688942-87696703 retained_intron
  ENSMUST00000172855 Msh2-005 87672609-87685566 protein_coding
  ENSMUST00000173097 Msh2-002 87672561-87709408 retained_intron
  ENSMUST00000174240 Msh2-003 87672540-87679692 retained_intron
  ENSMUST00000174703 Msh2-006 87696541-87717678 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000024967ENSMUST00000173097
Transcript ID C166 Tie2+ EC mES
ENSMUST00000024967 19.932±2.46 6.552±2.62 29.651±3.03
ENSMUST00000173097 N/A 1.657±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008D2 CIL_0008D2_0002 VISTA
CIL_0006KU CIL_0006KU_0002 CGP
CIL_0006KS CIL_0006KS_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 IBA nuclear chromosome
GO:0000287 IEA magnesium ion binding
GO:0000400 IBA four-way junction DNA binding
GO:0000403 IBA Y-form DNA binding
GO:0000404 IBA heteroduplex DNA loop binding
GO:0000406 IBA double-strand/single-strand DNA junction binding
GO:0000710 IBA meiotic mismatch repair
GO:0001701 IGI in utero embryonic development
GO:0002204 IGI somatic recombination of immunoglobulin genes involved in immune response
GO:0003677 ISS DNA binding
GO:0003684 IMP damaged DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003697 IEA single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006119 IMP oxidative phosphorylation
GO:0006200 IBA ATP catabolic process
GO:0006281 IMP DNA repair
GO:0006298 IMP mismatch repair
GO:0006301 ISS postreplication repair
GO:0006302 IMP double-strand break repair
GO:0006311 IBA meiotic gene conversion
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007050 IMP cell cycle arrest
GO:0007281 IMP germ cell development
GO:0008022 IEA protein C-terminus binding
GO:0008094 IBA DNA-dependent ATPase activity
GO:0008340 IMP determination of adult lifespan
GO:0008584 IMP male gonad development
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010165 IMP response to X-ray
GO:0010224 IMP response to UV-B
GO:0016020 IEA membrane
GO:0016446 IMP somatic hypermutation of immunoglobulin genes
GO:0016447 IMP somatic recombination of immunoglobulin gene segments
GO:0016887 IMP ATPase activity
GO:0019237 IDA centromeric DNA binding
GO:0019724 IMP B cell mediated immunity
GO:0019899 IEA enzyme binding
GO:0019901 IEA protein kinase binding
GO:0030183 IMP B cell differentiation
GO:0030983 IMP mismatched DNA binding
GO:0031573 IGI intra-S DNA damage checkpoint
GO:0032137 ISO guanine/thymine mispair binding
GO:0032138 IBA single base insertion or deletion binding
GO:0032139 IEA dinucleotide insertion or deletion binding
GO:0032142 IEA single guanine insertion binding
GO:0032143 IEA single thymine insertion binding
GO:0032181 IEA dinucleotide repeat insertion binding
GO:0032301 IDA MutSalpha complex
GO:0032302 IBA MutSbeta complex
GO:0032357 IEA oxidized purine DNA binding
GO:0032405 IEA MutLalpha complex binding
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042803 IEA protein homodimerization activity
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043531 IEA ADP binding
GO:0043570 IBA maintenance of DNA repeat elements
GO:0045128 IBA negative regulation of reciprocal meiotic recombination
GO:0045190 IMP isotype switching
GO:0045910 IMP negative regulation of DNA recombination
GO:0051096 IEA positive regulation of helicase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018022 msh2 protein_coding Danio_rerio
ENSG00000095002 MSH2 mutS homolog 2 protein_coding Homo_sapiens

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