ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024290 Rock1 10090 - 18:10064401-10181792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067947 Rock1-201 10064401-10181792 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000067947
Transcript ID C166 Tie2+ EC mES
ENSMUST00000067947 7.531±3.27 8.959±1.77 6.991±1.62

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00015E CIL_00015E_0002 CGP
CIL_0005O1 CIL_0005O1_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0003383 IGI apical constriction
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005794 IEA Golgi apparatus
GO:0005856 IDA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007266 ISO Rho protein signal transduction
GO:0016525 IEA negative regulation of angiogenesis
GO:0017048 IEA Rho GTPase binding
GO:0022614 IEA membrane to membrane docking
GO:0030027 IDA lamellipodium
GO:0030036 IGI actin cytoskeleton organization
GO:0032060 IMP bleb assembly
GO:0032970 IGI regulation of actin filament-based process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045616 IEA regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0050900 IEA leukocyte migration
GO:0050901 IEA leukocyte tethering or rolling
GO:0051451 IMP myoblast migration
GO:0051894 IMP positive regulation of focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058993 rock1 protein_coding Danio_rerio
ENSG00000067900 ROCK1 Rho-associated, coiled-coil containing protein kinase 1 protein_coding Homo_sapiens

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