ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024998 Plce1 10090 + 19:38481109-38785030 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000169713 Plce1-001 38524197-38785030 protein_coding
  ENSMUST00000181994 Plce1-006 38481109-38524066 processed_transcript
  ENSMUST00000182267 Plce1-003 38524209-38782795 protein_coding
  ENSMUST00000182481 Plce1-002 38481121-38783430 protein_coding
  ENSMUST00000182589 Plce1-004 38722370-38783588 retained_intron
  ENSMUST00000182999 Plce1-007 38583368-38652007 protein_coding
  ENSMUST00000183131 Plce1-005 38734914-38751123 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000169713ENSMUST00000182267ENSMUST00000182481ENSMUST00000182589
Transcript ID C166 Tie2+ EC mES
ENSMUST00000169713 5.236±0.54 0.014±0.00 0.069±0.02
ENSMUST00000182267 N/A 0.014±0.00 N/A
ENSMUST00000182481 22.278±2.82 N/A 0.207±0.13
ENSMUST00000182589 N/A 0.011±0.00 0.027±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00067K CIL_00067K_0002 CGP
CIL_00073K CIL_00073K_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 ISS activation of MAPK activity
GO:0004435 ISS phosphatidylinositol phospholipase C activity
GO:0004629 ISS phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0007200 ISS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008277 ISS regulation of G-protein coupled receptor protein signaling pathway
GO:0016042 IEA lipid catabolic process
GO:0019899 ISS enzyme binding
GO:0032835 IEA glomerulus development
GO:0043547 IEA positive regulation of GTPase activity
GO:0045859 ISS regulation of protein kinase activity
GO:0046578 ISS regulation of Ras protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087921 plce1 protein_coding Danio_rerio
ENSG00000138193 PLCE1 phospholipase C, epsilon 1 protein_coding Homo_sapiens

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