ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025001 Hells 10090 + 19:38930915-38971051 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025965 Hells-001 38930915-38971051 protein_coding
  ENSMUST00000127968 Hells-005 38943689-38950475 processed_transcript
  ENSMUST00000128949 Hells-002 38934508-38940601 retained_intron
  ENSMUST00000138292 Hells-004 38931030-38940500 retained_intron
  ENSMUST00000145051 Hells-003 38931174-38943914 protein_coding
  ENSMUST00000155465 Hells-006 38931390-38953609 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000025965ENSMUST00000127968
Transcript ID C166 Tie2+ EC mES
ENSMUST00000025965 21.796±6.22 2.344±1.38 3.650±2.21
ENSMUST00000127968 35.241±1.43 6.218±5.92 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003RX CIL_0003RX_0002 CGP
CIL_00067G CIL_00067G_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000775 IDA chromosome, centromeric region
GO:0001655 IMP urogenital system development
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005721 IDA pericentric heterochromatin
GO:0006306 IMP DNA methylation
GO:0006342 IMP chromatin silencing
GO:0006346 IMP methylation-dependent chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0007067 IEA mitotic nuclear division
GO:0007275 IMP multicellular organismal development
GO:0010216 IMP maintenance of DNA methylation
GO:0030098 TAS lymphocyte differentiation
GO:0031508 IMP pericentric heterochromatin assembly
GO:0043066 IMP negative regulation of apoptotic process
GO:0046651 IEP lymphocyte proliferation
GO:2001243 IMP negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057738 hells protein_coding Danio_rerio
ENSG00000119969 HELLS helicase, lymphoid-specific protein_coding Homo_sapiens

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