ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025902 Sox17 10090 - 1:4490931-4497354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027035 Sox17-001 4490931-4496413 protein_coding
  ENSMUST00000116652 Sox17-002 4491713-4496363 protein_coding
  ENSMUST00000191647 Sox17-007 4492458-4496330 protein_coding
  ENSMUST00000191939 Sox17-006 4492465-4493735 protein_coding
  ENSMUST00000192505 Sox17-008 4492457-4493604 retained_intron
  ENSMUST00000192650 Sox17-004 4491390-4497354 protein_coding
  ENSMUST00000192913 Sox17-003 4492467-4496396 protein_coding
  ENSMUST00000195555 Sox17-005 4491250-4496757 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECmESENSMUST00000027035ENSMUST00000116652ENSMUST00000191939ENSMUST00000195555
Transcript ID Tie2+ EC mES
ENSMUST00000027035 19.529±6.19 1.572±0.55
ENSMUST00000116652 21.682±0.00 N/A
ENSMUST00000191939 35.205±0.00 N/A
ENSMUST00000195555 24.239±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00053S CIL_00053S_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001525 IGI angiogenesis
GO:0001570 IGI vasculogenesis
GO:0001706 IEA endoderm formation
GO:0001828 IMP inner cell mass cellular morphogenesis
GO:0001947 IMP heart looping
GO:0003142 IMP cardiogenic plate morphogenesis
GO:0003143 IMP embryonic heart tube morphogenesis
GO:0003151 IGI outflow tract morphogenesis
GO:0003308 IMP negative regulation of Wnt signaling pathway involved in heart development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007283 IDA spermatogenesis
GO:0007369 IMP gastrulation
GO:0007492 IMP endoderm development
GO:0007493 IDA endodermal cell fate determination
GO:0008013 IEA beta-catenin binding
GO:0008134 IEA transcription factor binding
GO:0010628 IMP positive regulation of gene expression
GO:0021903 IMP rostrocaudal neural tube patterning
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0030308 IEA negative regulation of cell growth
GO:0031648 IEA protein destabilization
GO:0035050 IGI embryonic heart tube development
GO:0042074 IMP cell migration involved in gastrulation
GO:0042661 IMP regulation of mesodermal cell fate specification
GO:0042662 IMP negative regulation of mesodermal cell fate specification
GO:0042789 IEA mRNA transcription from RNA polymerase II promoter
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045595 IMP regulation of cell differentiation
GO:0045597 IDA positive regulation of cell differentiation
GO:0045732 IDA positive regulation of protein catabolic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045995 IMP regulation of embryonic development
GO:0046982 IDA protein heterodimerization activity
GO:0048568 IMP embryonic organ development
GO:0048617 IMP embryonic foregut morphogenesis
GO:0048643 IDA positive regulation of skeletal muscle tissue development
GO:0048863 IMP stem cell differentiation
GO:0048866 IDA stem cell fate specification
GO:0050821 IEA protein stabilization
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060214 IGI endocardium formation
GO:0060807 IMP regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification
GO:0060913 IEA cardiac cell fate determination
GO:0060956 IGI endocardial cell differentiation
GO:0061009 IMP common bile duct development
GO:0061010 IMP gall bladder development
GO:0061031 IMP endodermal digestive tract morphogenesis
GO:0072001 IEA renal system development
GO:0072091 IDA regulation of stem cell proliferation
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:2000035 IMP regulation of stem cell division
GO:2000043 IMP regulation of cardiac cell fate specification

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000164736 SOX17 SRY (sex determining region Y)-box 17 protein_coding Homo_sapiens

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