ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025958 Creb1 10090 + 1:64532645-64604548 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049932 Creb1-004 64532809-64601257 protein_coding
  ENSMUST00000087366 Creb1-001 64532819-64604548 protein_coding
  ENSMUST00000171164 Creb1-008 64532797-64597571 protein_coding
  ENSMUST00000185594 Creb1-002 64532645-64597695 protein_coding
  ENSMUST00000186335 Creb1-005 64532832-64575113 processed_transcript
  ENSMUST00000187035 Creb1-010 64560925-64562566 retained_intron
  ENSMUST00000187811 Creb1-003 64532809-64578216 protein_coding
  ENSMUST00000188855 Creb1-011 64532804-64558939 retained_intron
  ENSMUST00000190348 Creb1-007 64532894-64597477 protein_coding
  ENSMUST00000190876 Creb1-006 64532859-64597467 nonsense_mediated_decay
  ENSMUST00000190979 Creb1-009 64576388-64579150 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000049932ENSMUST00000087366ENSMUST00000187811ENSMUST00000190348
Transcript ID C166 Tie2+ EC mES
ENSMUST00000049932 5.880±0.39 3.294±0.61 N/A
ENSMUST00000087366 5.953±0.46 4.399±0.90 2.923±0.97
ENSMUST00000187811 N/A 15.972±1.27 N/A
ENSMUST00000190348 N/A 12.272±3.38 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006YW CIL_0006YW_0002 CGP
CIL_0006YR CIL_0006YR_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005719 IEA nuclear euchromatin
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006468 ISO protein phosphorylation
GO:0007409 IMP axonogenesis
GO:0007595 IMP lactation
GO:0007613 IMP memory
GO:0007623 IDA circadian rhythm
GO:0008361 IGI regulation of cell size
GO:0010033 ISO response to organic substance
GO:0010944 IEA negative regulation of transcription by competitive promoter binding
GO:0019899 IEA enzyme binding
GO:0021983 IMP pituitary gland development
GO:0030879 IMP mammary gland development
GO:0033363 IMP secretory granule organization
GO:0033762 IMP response to glucagon
GO:0035497 IEA cAMP response element binding
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0042493 IDA response to drug
GO:0043565 IDA sequence-specific DNA binding
GO:0045600 IGI positive regulation of fat cell differentiation
GO:0045672 IDA positive regulation of osteoclast differentiation
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046887 IMP positive regulation of hormone secretion
GO:0046889 IGI positive regulation of lipid biosynthetic process
GO:0050821 IMP protein stabilization
GO:0060428 IMP lung epithelium development
GO:0060430 IMP lung saccule development
GO:0060509 IMP Type I pneumocyte differentiation
GO:0071294 IDA cellular response to zinc ion
GO:0071363 IDA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053586 creb1a protein_coding Danio_rerio
ENSDARG00000093420 creb1b protein_coding Danio_rerio
ENSG00000118260 CREB1 cAMP responsive element binding protein 1 protein_coding Homo_sapiens

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