ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026177 Slc11a1 10090 + 1:74375195-74386062 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027368 Slc11a1-001 74375203-74386062 protein_coding
  ENSMUST00000127487 Slc11a1-008 74383034-74383834 retained_intron
  ENSMUST00000131511 Slc11a1-003 74375225-74386051 retained_intron
  ENSMUST00000133896 Slc11a1-007 74381651-74384173 retained_intron
  ENSMUST00000134189 Slc11a1-010 74383600-74385197 processed_transcript
  ENSMUST00000135137 Slc11a1-005 74375572-74376890 processed_transcript
  ENSMUST00000136786 Slc11a1-004 74375253-74381826 processed_transcript
  ENSMUST00000147233 Slc11a1-002 74375203-74386052 retained_intron
  ENSMUST00000149166 Slc11a1-009 74383341-74384173 processed_transcript
  ENSMUST00000155865 Slc11a1-006 74376657-74379856 processed_transcript
  ENSMUST00000187516 Slc11a1-011 74375195-74385755 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000027368ENSMUST00000131511ENSMUST00000133896ENSMUST00000134189ENSMUST00000136786ENSMUST00000147233ENSMUST00000187516
Transcript ID C166 Tie2+ EC mES
ENSMUST00000027368 0.016±0.00 0.086±0.03 0.072±0.03
ENSMUST00000131511 N/A 0.033±0.00 N/A
ENSMUST00000133896 0.155±0.00 N/A N/A
ENSMUST00000134189 N/A 0.361±0.14 N/A
ENSMUST00000136786 0.009±0.00 N/A N/A
ENSMUST00000147233 N/A 0.058±0.00 N/A
ENSMUST00000187516 0.039±0.00 0.027±0.02 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00054V CIL_00054V_0002 CGP
CIL_0005VF CIL_0005VF_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IMP protein import into nucleus, translocation
GO:0000165 ISO MAPK cascade
GO:0001818 IMP negative regulation of cytokine production
GO:0001819 IMP positive regulation of cytokine production
GO:0002309 IMP T cell proliferation involved in immune response
GO:0002369 IMP T cell cytokine production
GO:0002606 IMP positive regulation of dendritic cell antigen processing and presentation
GO:0002827 IMP positive regulation of T-helper 1 type immune response
GO:0005384 IMP manganese ion transmembrane transporter activity
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005886 IEA plasma membrane
GO:0006826 IMP iron ion transport
GO:0006828 IMP manganese ion transport
GO:0006876 IEA cellular cadmium ion homeostasis
GO:0006879 IMP cellular iron ion homeostasis
GO:0006909 IMP phagocytosis
GO:0006954 IMP inflammatory response
GO:0007035 IMP vacuolar acidification
GO:0009279 IDA cell outer membrane
GO:0009617 IMP response to bacterium
GO:0010008 IDA endosome membrane
GO:0010628 IMP positive regulation of gene expression
GO:0015707 IDA nitrite transport
GO:0016021 IEA integral component of membrane
GO:0030670 IDA phagocytic vesicle membrane
GO:0032147 IMP activation of protein kinase activity
GO:0032496 ISO response to lipopolysaccharide
GO:0032623 IMP interleukin-2 production
GO:0032632 IMP interleukin-3 production
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0034341 IDA response to interferon-gamma
GO:0042060 IMP wound healing
GO:0042116 IMP macrophage activation
GO:0042742 IMP defense response to bacterium
GO:0042803 IEA protein homodimerization activity
GO:0042832 IMP defense response to protozoan
GO:0043091 IDA L-arginine import
GO:0045342 IMP MHC class II biosynthetic process
GO:0045730 IDA respiratory burst
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046915 IEA transition metal ion transmembrane transporter activity
GO:0048002 IMP antigen processing and presentation of peptide antigen
GO:0048255 IMP mRNA stabilization
GO:0050766 IMP positive regulation of phagocytosis
GO:0050829 IMP defense response to Gram-negative bacterium
GO:0051139 IEA metal ion:proton antiporter activity
GO:0055072 IMP iron ion homeostasis
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0070574 IEA cadmium ion transmembrane transport
GO:0070821 IEA tertiary granule membrane
GO:0070839 IDA divalent metal ion export
GO:0071421 IMP manganese ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000018280 SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 protein_coding Homo_sapiens

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