ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026770 Il2ra 10090 + 2:11642807-11693193 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028111 Il2ra-001 11642807-11693193 protein_coding
  ENSMUST00000150890 Il2ra-002 11642849-11648768 protein_coding
  ENSMUST00000195427 Il2ra-003 11679708-11680209 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000028111ENSMUST00000150890
Transcript ID C166 Tie2+ EC mES
ENSMUST00000028111 0.004±0.00 0.053±0.04 0.045±0.01
ENSMUST00000150890 N/A 0.086±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0004911 IMP interleukin-2 receptor activity
GO:0005515 IPI protein binding
GO:0006924 IMP activation-induced cell death of T cells
GO:0007219 IGI Notch signaling pathway
GO:0008144 IEA drug binding
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0019976 IPI interleukin-2 binding
GO:0038110 IMP interleukin-2-mediated signaling pathway
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042104 IMP positive regulation of activated T cell proliferation
GO:0042130 IMP negative regulation of T cell proliferation
GO:0043029 IMP T cell homeostasis
GO:0045582 IEA positive regulation of T cell differentiation
GO:0046013 IMP regulation of T cell homeostatic proliferation
GO:0050672 IMP negative regulation of lymphocyte proliferation
GO:0050687 IEA negative regulation of defense response to virus
GO:0050728 IMP negative regulation of inflammatory response
GO:0050777 IEA negative regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000134460 IL2RA interleukin 2 receptor, alpha protein_coding Homo_sapiens

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