ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026842 Abl1 10090 + 2:31688376-31804227 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028190 Abl1-008 31759943-31804227 protein_coding
  ENSMUST00000075759 Abl1-001 31688551-31803541 protein_coding
  ENSMUST00000123471 Abl1-004 31689465-31778392 protein_coding
  ENSMUST00000124089 Abl1-009 31760173-31779024 protein_coding
  ENSMUST00000124726 Abl1-011 31796646-31797992 retained_intron
  ENSMUST00000127714 Abl1-010 31790171-31794570 retained_intron
  ENSMUST00000135233 Abl1-005 31689611-31779024 nonsense_mediated_decay
  ENSMUST00000142554 Abl1-007 31688552-31800339 nonsense_mediated_decay
  ENSMUST00000146537 Abl1-002 31688376-31698336 retained_intron
  ENSMUST00000156736 Abl1-003 31688537-31707082 processed_transcript

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000028190ENSMUST00000075759ENSMUST00000142554ENSMUST00000146537
Transcript ID C166 Tie2+ EC mES
ENSMUST00000028190 32.974±2.67 5.629±3.83 11.968±3.10
ENSMUST00000075759 19.903±2.74 7.191±2.91 2.684±0.27
ENSMUST00000142554 N/A 4.436±0.00 N/A
ENSMUST00000146537 N/A 1.474±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000936 CIL_000936_0002 VISTA
CIL_0008XQ CIL_0008XQ_0002 VISTA
CIL_0007CW CIL_0007CW_0003 CGP
CIL_0006I2 CIL_0006I2_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0001922 IMP B-1 B cell homeostasis
GO:0002322 IMP B cell proliferation involved in immune response
GO:0002333 IMP transitional one stage B cell differentiation
GO:0003677 IEA DNA binding
GO:0004672 IDA protein kinase activity
GO:0004713 IMP protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 ISA cytosol
GO:0006281 IEA DNA repair
GO:0006909 IMP phagocytosis
GO:0006914 IEA autophagy
GO:0006915 IEA apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0006975 IEA DNA damage induced protein phosphorylation
GO:0006979 IMP response to oxidative stress
GO:0007173 IGI epidermal growth factor receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0008022 IEA protein C-terminus binding
GO:0015629 IDA actin cytoskeleton
GO:0016301 IDA kinase activity
GO:0017124 IEA SH3 domain binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019904 IPI protein domain specific binding
GO:0019905 IEA syntaxin binding
GO:0021587 IGI cerebellum morphogenesis
GO:0022408 IGI negative regulation of cell-cell adhesion
GO:0030035 IDA microspike assembly
GO:0030036 IDA actin cytoskeleton organization
GO:0030145 IDA manganese ion binding
GO:0030514 IMP negative regulation of BMP signaling pathway
GO:0031252 IDA cell leading edge
GO:0032956 IGI regulation of actin cytoskeleton organization
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0042100 IMP B cell proliferation
GO:0042770 ISS signal transduction in response to DNA damage
GO:0043065 IMP positive regulation of apoptotic process
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0045931 IGI positive regulation of mitotic cell cycle
GO:0046632 IGI alpha-beta T cell differentiation
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048536 IMP spleen development
GO:0048538 IMP thymus development
GO:0048668 IMP collateral sprouting
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0050798 IMP activated T cell proliferation
GO:0050853 IMP B cell receptor signaling pathway
GO:0050885 IGI neuromuscular process controlling balance
GO:0051015 IDA actin filament binding
GO:0051019 IEA mitogen-activated protein kinase binding
GO:0051281 IGI positive regulation of release of sequestered calcium ion into cytosol
GO:0051353 IEA positive regulation of oxidoreductase activity
GO:0051444 IEA negative regulation of ubiquitin-protein transferase activity
GO:0051726 IDA regulation of cell cycle
GO:0060020 IGI Bergmann glial cell differentiation
GO:0070064 ISS proline-rich region binding
GO:0070373 IMP negative regulation of ERK1 and ERK2 cascade
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity
GO:0090135 IMP actin filament branching
GO:1900042 IGI positive regulation of interleukin-2 secretion
GO:1900275 IEA negative regulation of phospholipase C activity
GO:1901216 IMP positive regulation of neuron death
GO:1902715 IGI positive regulation of interferon-gamma secretion
GO:1903053 IGI regulation of extracellular matrix organization
GO:2000096 IGI positive regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000352 IGI negative regulation of endothelial cell apoptotic process
GO:2000772 IGI regulation of cellular senescence
GO:2000773 IGI negative regulation of cellular senescence
GO:2001020 IEA regulation of response to DNA damage stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035187 abl1 protein_coding Danio_rerio
ENSG00000097007 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase protein_coding Homo_sapiens

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