ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028048 Gba 10090 + 3:89202928-89208966 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077367 Gba-003 89202928-89208679 protein_coding
  ENSMUST00000167998 Gba-002 89202940-89208681 protein_coding
  ENSMUST00000196887 Gba-004 89208217-89208966 retained_intron
  ENSMUST00000197738 Gba-001 89202936-89208681 nonsense_mediated_decay
  ENSMUST00000200124 Gba-005 89205485-89206388 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000077367ENSMUST00000167998ENSMUST00000196887
Transcript ID C166 Tie2+ EC mES
ENSMUST00000077367 23.338±3.36 21.395±14.53 7.771±1.29
ENSMUST00000167998 6.599±1.53 N/A 1.258±0.00
ENSMUST00000196887 N/A N/A 15.566±5.73

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004348 IEA glucosylceramidase activity
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005765 IDA lysosomal membrane
GO:0005975 IEA carbohydrate metabolic process
GO:0006680 IEA glucosylceramide catabolic process
GO:0009268 IEA response to pH
GO:0023021 IEA termination of signal transduction
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0033561 IEA regulation of water loss via skin
GO:0033574 IEA response to testosterone
GO:0035307 IEA positive regulation of protein dephosphorylation
GO:0043202 IDA lysosomal lumen
GO:0043407 IEA negative regulation of MAP kinase activity
GO:0043589 IEA skin morphogenesis
GO:0043627 IEA response to estrogen
GO:0046512 IEA sphingosine biosynthetic process
GO:0046513 IEA ceramide biosynthetic process
GO:0051384 IEA response to glucocorticoid
GO:0070062 IEA extracellular vesicular exosome
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0097066 IEA response to thyroid hormone

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076058 gba protein_coding Danio_rerio
ENSG00000177628 GBA glucosidase, beta, acid protein_coding Homo_sapiens

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