ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028063 Lmna 10090 - 3:88480147-88509956 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029699 Lmna-001 88481148-88503335 protein_coding
  ENSMUST00000036252 Lmna-003 88483206-88493312 protein_coding
  ENSMUST00000120377 Lmna-002 88483205-88503307 protein_coding
  ENSMUST00000135494 Lmna-005 88481846-88503337 processed_transcript
  ENSMUST00000147537 Lmna-006 88480147-88484607 retained_intron
  ENSMUST00000149068 Lmna-004 88502753-88509956 protein_coding
  ENSMUST00000150496 Lmna-007 88482077-88482864 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000029699ENSMUST00000036252ENSMUST00000120377ENSMUST00000147537
Transcript ID C166 Tie2+ EC mES
ENSMUST00000029699 35.373±3.47 6.826±3.38 1.828±0.29
ENSMUST00000036252 N/A 7.573±0.00 7.917±3.72
ENSMUST00000120377 49.733±10.71 23.472±15.18 4.004±1.88
ENSMUST00000147537 N/A 1.932±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008P5 CIL_0008P5_0002 VISTA
CIL_000898 CIL_000898_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005638 IDA lamin filament
GO:0005737 IEA cytoplasm
GO:0006997 IMP nucleus organization
GO:0006998 IGI nuclear envelope organization
GO:0007517 ISS muscle organ development
GO:0030010 NAS establishment of cell polarity
GO:0030334 IMP regulation of cell migration
GO:0030951 IMP establishment or maintenance of microtubule cytoskeleton polarity
GO:0034504 IMP protein localization to nucleus
GO:0035105 IMP sterol regulatory element binding protein import into nucleus
GO:0048471 ISS perinuclear region of cytoplasm
GO:0055015 IMP ventricular cardiac muscle cell development
GO:0071456 ISS cellular response to hypoxia
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria
GO:0090343 ISS positive regulation of cell aging
GO:1900180 IMP regulation of protein localization to nucleus
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013415 lmna protein_coding Danio_rerio
ENSG00000160789 LMNA lamin A/C protein_coding Homo_sapiens

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