ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028664 Ephb2 10090 - 4:136647539-136835988 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000059287 Ephb2-002 136653608-136835956 protein_coding
  ENSMUST00000105845 Ephb2-001 136647539-136835988 protein_coding
  ENSMUST00000105846 Ephb2-003 136654646-136835843 protein_coding
  ENSMUST00000144573 Ephb2-005 136769392-136835974 retained_intron
  ENSMUST00000151502 Ephb2-006 136659687-136661652 retained_intron
  ENSMUST00000156558 Ephb2-004 136661463-136694040 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000059287ENSMUST00000105845ENSMUST00000105846ENSMUST00000151502
Transcript ID C166 Tie2+ EC mES
ENSMUST00000059287 3.191±0.66 0.040±0.01 3.589±0.93
ENSMUST00000105845 0.514±0.06 0.050±0.00 0.542±0.16
ENSMUST00000105846 4.034±0.73 0.019±0.00 1.521±0.42
ENSMUST00000151502 N/A 0.382±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000209 CIL_000209_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IGI cell morphogenesis
GO:0004872 IDA receptor activity
GO:0005003 IDA ephrin receptor activity
GO:0005005 TAS transmembrane-ephrin receptor activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 IDA axon guidance
GO:0007612 IMP learning
GO:0008046 IDA axon guidance receptor activity
GO:0009887 IMP organ morphogenesis
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0021631 IMP optic nerve morphogenesis
GO:0021952 IMP central nervous system projection neuron axonogenesis
GO:0031290 IDA retinal ganglion cell axon guidance
GO:0043025 IDA neuronal cell body
GO:0048013 IDA ephrin receptor signaling pathway
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:0048170 IMP positive regulation of long-term neuronal synaptic plasticity
GO:0048593 IMP camera-type eye morphogenesis
GO:0050770 IDA regulation of axonogenesis
GO:0050771 IDA negative regulation of axonogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021539 ephb2b protein_coding Danio_rerio
ENSDARG00000037373 ephb2a protein_coding Danio_rerio
ENSG00000133216 EPHB2 EPH receptor B2 protein_coding Homo_sapiens

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