ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029470 P2rx4 10090 + 5:122707544-122729738 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031429 P2rx4-001 122707544-122729738 protein_coding
  ENSMUST00000081554 P2rx4-002 122707584-122729044 protein_coding
  ENSMUST00000132062 P2rx4-006 122724655-122725265 retained_intron
  ENSMUST00000139631 P2rx4-003 122707654-122728323 protein_coding
  ENSMUST00000139712 P2rx4-007 122727664-122728585 processed_transcript
  ENSMUST00000142664 P2rx4-004 122707654-122728323 protein_coding
  ENSMUST00000152337 P2rx4-005 122707570-122719477 retained_intron
  ENSMUST00000195963 P2rx4-008 122707569-122711463 retained_intron
  ENSMUST00000198560 P2rx4-009 122707580-122725366 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000031429ENSMUST00000081554ENSMUST00000132062ENSMUST00000142664ENSMUST00000195963
Transcript ID C166 Tie2+ EC mES
ENSMUST00000031429 3.110±0.49 2.016±2.15 N/A
ENSMUST00000081554 15.376±1.68 3.773±2.01 0.335±0.05
ENSMUST00000132062 N/A N/A 1.524±0.29
ENSMUST00000142664 9.947±1.35 3.075±0.00 N/A
ENSMUST00000195963 N/A 0.900±0.33 0.120±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002ZL CIL_0002ZL_0002 CGP
CIL_0002ZK CIL_0002ZK_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001614 IBA purinergic nucleotide receptor activity
GO:0002028 IEA regulation of sodium ion transport
GO:0004931 IMP extracellular ATP-gated cation channel activity
GO:0005102 IEA receptor binding
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005765 IEA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006809 IDA nitric oxide biosynthetic process
GO:0006810 IEA transport
GO:0006816 IMP calcium ion transport
GO:0007165 IEA signal transduction
GO:0008144 IEA drug binding
GO:0008217 IEA regulation of blood pressure
GO:0008270 IEA zinc ion binding
GO:0010524 IEA positive regulation of calcium ion transport into cytosol
GO:0010614 IEA negative regulation of cardiac muscle hypertrophy
GO:0014069 IEA postsynaptic density
GO:0019228 IEA neuronal action potential
GO:0019233 IEA sensory perception of pain
GO:0030054 IEA cell junction
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0033198 IEA response to ATP
GO:0034220 IEA ion transmembrane transport
GO:0034405 IEA response to fluid shear stress
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0042311 IMP vasodilation
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0045177 IDA apical part of cell
GO:0045202 IEA synapse
GO:0045296 IEA cadherin binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050850 IEA positive regulation of calcium-mediated signaling
GO:0051260 IEA protein homooligomerization
GO:0051899 IEA membrane depolarization
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0055119 IEA relaxation of cardiac muscle
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0070062 IEA extracellular vesicular exosome
GO:0071318 IEA cellular response to ATP
GO:0097190 IEA apoptotic signaling pathway
GO:0098655 IMP cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042452 p2rx4b protein_coding Danio_rerio
ENSDARG00000044752 p2rx4a protein_coding Danio_rerio
ENSG00000135124 P2RX4 purinergic receptor P2X, ligand-gated ion channel, 4 protein_coding Homo_sapiens

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