ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030671 Pde3b 10090 + 7:114415281-114539251 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032909 Pde3b-001 114415281-114539251 protein_coding
  ENSMUST00000140007 Pde3b-002 114506178-114508463 retained_intron
  ENSMUST00000149455 Pde3b-003 114521734-114531022 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000032909
Transcript ID C166 Tie2+ EC mES
ENSMUST00000032909 7.124±2.69 0.391±0.13 3.152±0.15

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003ZT CIL_0003ZT_0002 CGP
CIL_0003ZS CIL_0003ZS_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0006198 IEA cAMP catabolic process
GO:0007162 IEA negative regulation of cell adhesion
GO:0007165 IEA signal transduction
GO:0016020 IEA membrane
GO:0016525 IEA negative regulation of angiogenesis
GO:0031018 IDA endocrine pancreas development
GO:0032045 IEA guanyl-nucleotide exchange factor complex
GO:0042593 IDA glucose homeostasis
GO:0046872 IEA metal ion binding
GO:0050796 IDA regulation of insulin secretion
GO:0050995 IEA negative regulation of lipid catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062190 PDE3B protein_coding Danio_rerio
ENSG00000152270 PDE3B phosphodiesterase 3B, cGMP-inhibited protein_coding Homo_sapiens

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