ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031162 Gata1 10090 - X:7959260-7978071 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033502 Gata1-001 7959260-7967910 protein_coding
  ENSMUST00000125418 Gata1-002 7962440-7978071 protein_coding
  ENSMUST00000128449 Gata1-003 7963029-7964166 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000033502ENSMUST00000125418
Transcript ID C166 Tie2+ EC mES
ENSMUST00000033502 N/A 0.019±0.00 3.685±0.35
ENSMUST00000125418 0.040±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00029K CIL_00029K_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001701 IMP in utero embryonic development
GO:0002039 IPI p53 binding
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007267 IMP cell-cell signaling
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0008301 IDA DNA binding, bending
GO:0008584 IEA male gonad development
GO:0010559 IMP regulation of glycoprotein biosynthetic process
GO:0010724 IDA regulation of definitive erythrocyte differentiation
GO:0017053 IEA transcriptional repressor complex
GO:0030099 IMP myeloid cell differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030219 IGI megakaryocyte differentiation
GO:0030220 IMP platelet formation
GO:0030221 IEA basophil differentiation
GO:0030222 IEA eosinophil differentiation
GO:0030502 IMP negative regulation of bone mineralization
GO:0031490 ISS chromatin DNA binding
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0035162 IMP embryonic hemopoiesis
GO:0035854 IEA eosinophil fate commitment
GO:0043066 IMP negative regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045648 IEA positive regulation of erythrocyte differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IMP cell development
GO:0048821 IEA erythrocyte development
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0070527 IMP platelet aggregation
GO:0070742 IEA C2H2 zinc finger domain binding
GO:0071733 IDA transcriptional activation by promoter-enhancer looping
GO:0097028 IDA dendritic cell differentiation
GO:0097067 IEA cellular response to thyroid hormone stimulus
GO:2000678 IEA negative regulation of transcription regulatory region DNA binding
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013477 gata1a protein_coding Danio_rerio
ENSDARG00000059130 gata1b protein_coding Danio_rerio
ENSG00000102145 GATA1 GATA binding protein 1 (globin transcription factor 1) protein_coding Homo_sapiens

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