ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032113 Chek1 10090 - 9:36708482-36727065 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034625 Chek1-201 36708482-36726658 protein_coding
  ENSMUST00000172702 Chek1-002 36708482-36726374 protein_coding
  ENSMUST00000172742 Chek1-003 36723862-36726451 protein_coding
  ENSMUST00000173534 Chek1-006 36710157-36725868 protein_coding
  ENSMUST00000173796 Chek1-008 36722649-36727065 processed_transcript
  ENSMUST00000173963 Chek1-005 36710157-36725868 protein_coding
  ENSMUST00000173977 Chek1-009 36723603-36726570 retained_intron
  ENSMUST00000174105 Chek1-004 36709440-36726585 nonsense_mediated_decay
  ENSMUST00000174794 Chek1-010 36713744-36722745 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000034625ENSMUST00000172702ENSMUST00000173534ENSMUST00000173963ENSMUST00000174105ENSMUST00000174794
Transcript ID C166 Tie2+ EC mES
ENSMUST00000034625 1.908±0.53 0.364±0.03 3.650±1.89
ENSMUST00000172702 1.750±0.27 0.406±0.33 N/A
ENSMUST00000173534 2.878±0.00 N/A N/A
ENSMUST00000173963 4.434±1.02 2.332±2.16 N/A
ENSMUST00000174105 7.299±1.48 0.484±0.45 2.926±0.55
ENSMUST00000174794 N/A 6.258±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000086 IMP G2/M transition of mitotic cell cycle
GO:0000781 IEA chromosome, telomeric region
GO:0000785 IDA chromatin
GO:0000794 ISS condensed nuclear chromosome
GO:0004672 IMP protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005657 IDA replication fork
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0006281 IDA DNA repair
GO:0006468 IDA protein phosphorylation
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006975 ISS DNA damage induced protein phosphorylation
GO:0010468 IGI regulation of gene expression
GO:0010569 ISS regulation of double-strand break repair via homologous recombination
GO:0010767 IMP regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
GO:0010972 IEA negative regulation of G2/M transition of mitotic cell cycle
GO:0018107 ISS peptidyl-threonine phosphorylation
GO:0031572 ISS G2 DNA damage checkpoint
GO:0035402 IDA histone kinase activity (H3-T11 specific)
GO:0035407 IDA histone H3-T11 phosphorylation
GO:0042127 IMP regulation of cell proliferation
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045839 ISS negative regulation of mitosis
GO:0046602 ISS regulation of mitotic centrosome separation
GO:0048096 IMP chromatin-mediated maintenance of transcription
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071310 IEA cellular response to organic substance
GO:0071313 IEA cellular response to caffeine
GO:2000279 IEA negative regulation of DNA biosynthetic process
GO:2000615 IDA regulation of histone H3-K9 acetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000149554 CHEK1 checkpoint kinase 1 protein_coding Homo_sapiens

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