ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032177 Pde4a 10090 + 9:21165714-21213248 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003395 Pde4a-003 21196705-21211627 protein_coding
  ENSMUST00000039413 Pde4a-001 21165714-21213248 protein_coding
  ENSMUST00000115458 Pde4a-002 21184103-21211627 protein_coding
  ENSMUST00000127821 Pde4a-006 21192197-21194759 retained_intron
  ENSMUST00000131769 Pde4a-004 21181616-21211627 retained_intron
  ENSMUST00000140440 Pde4a-005 21184101-21193498 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000003395ENSMUST00000039413ENSMUST00000115458ENSMUST00000131769
Transcript ID C166 Tie2+ EC mES
ENSMUST00000003395 N/A 0.180±0.00 N/A
ENSMUST00000039413 2.668±0.95 0.400±0.21 2.442±0.72
ENSMUST00000115458 1.302±0.00 0.069±0.00 N/A
ENSMUST00000131769 1.685±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00037J CIL_00037J_0002 CGP
CIL_0004FB CIL_0004FB_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IDA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 ISS 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0007608 IGI sensory perception of smell
GO:0010738 IMP regulation of protein kinase A signaling
GO:0030552 IEA cAMP binding
GO:0035690 IDA cellular response to drug
GO:0043949 IMP regulation of cAMP-mediated signaling
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032344 pde4a protein_coding Danio_rerio
ENSG00000065989 PDE4A phosphodiesterase 4A, cAMP-specific protein_coding Homo_sapiens

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