ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032238 Rora 10090 + 9:68653786-69388246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034766 Rora-001 68653786-69388246 protein_coding
  ENSMUST00000113624 Rora-002 69289682-69379809 protein_coding
  ENSMUST00000132355 Rora-005 69195541-69250834 processed_transcript
  ENSMUST00000140351 Rora-003 68653786-68664967 processed_transcript
  ENSMUST00000143507 Rora-004 68655303-68664180 processed_transcript
  ENSMUST00000174296 Rora-006 68653891-69364494 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000034766ENSMUST00000113624
Transcript ID C166 Tie2+ EC mES
ENSMUST00000034766 0.244±0.09 1.106±0.56 N/A
ENSMUST00000113624 0.615±0.02 N/A 1.184±0.18

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008YJ CIL_0008YJ_0002 VISTA
CIL_0005GZ CIL_0005GZ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001046 IEA core promoter sequence-specific DNA binding
GO:0001222 IEA transcription corepressor binding
GO:0001223 IPI transcription coactivator binding
GO:0001525 ISS angiogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006805 IMP xenobiotic metabolic process
GO:0006809 IMP nitric oxide biosynthetic process
GO:0007623 IEA circadian rhythm
GO:0008013 IPI beta-catenin binding
GO:0008134 IEA transcription factor binding
GO:0008142 ISS oxysterol binding
GO:0008270 IEA zinc ion binding
GO:0008589 IMP regulation of smoothened signaling pathway
GO:0010575 ISS positive regulation vascular endothelial growth factor production
GO:0010906 IMP regulation of glucose metabolic process
GO:0019218 IMP regulation of steroid metabolic process
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0021930 IMP cerebellar granule cell precursor proliferation
GO:0030522 ISS intracellular receptor signaling pathway
GO:0032922 IDA circadian regulation of gene expression
GO:0036315 ISS cellular response to sterol
GO:0042692 ISS muscle cell differentiation
GO:0042752 IMP regulation of circadian rhythm
GO:0042753 IDA positive regulation of circadian rhythm
GO:0043030 IMP regulation of macrophage activation
GO:0043124 ISS negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 ISS sequence-specific DNA binding
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046068 IMP cGMP metabolic process
GO:0050728 ISS negative regulation of inflammatory response
GO:0060850 IDA regulation of transcription involved in cell fate commitment
GO:0070328 IMP triglyceride homeostasis
GO:0071456 ISS cellular response to hypoxia
GO:0072539 IMP T-helper 17 cell differentiation
GO:0098531 ISS direct ligand regulated sequence-specific DNA binding transcription factor activity
GO:2000188 IMP regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031768 roraa protein_coding Danio_rerio
ENSG00000069667 RORA RAR-related orphan receptor A protein_coding Homo_sapiens

Loading