ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032511 Scn5a 10090 - 9:119483408-119579016 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065196 Scn5a-201 119483408-119562678 protein_coding
  ENSMUST00000117911 Scn5a-001 119483410-119579016 protein_coding
  ENSMUST00000120420 Scn5a-002 119484324-119579016 protein_coding
  ENSMUST00000138934 Scn5a-003 119562537-119563503 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000065196ENSMUST00000120420
Transcript ID C166 Tie2+ EC mES
ENSMUST00000065196 0.007±0.00 0.004±0.00 N/A
ENSMUST00000120420 0.003±0.00 0.010±0.01 0.019±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008BE CIL_0008BE_0002 VISTA
CIL_0005VU CIL_0005VU_0002 CGP
CIL_0004RF CIL_0004RF_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IC voltage-gated sodium channel complex
GO:0003231 IMP cardiac ventricle development
GO:0005248 IDA voltage-gated sodium channel activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005886 IDA plasma membrane
GO:0006814 IDA sodium ion transport
GO:0009986 IDA cell surface
GO:0014070 IMP response to organic cyclic compound
GO:0014704 IDA intercalated disc
GO:0016021 ISS integral component of membrane
GO:0019228 IBA neuronal action potential
GO:0030315 IDA T-tubule
GO:0034706 IPI sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA:IDA sodium ion transmembrane transport
GO:0071277 ISS cellular response to calcium ion
GO:0086004 IMP regulation of cardiac muscle cell contraction
GO:0086006 IMP voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 IMP membrane depolarization during cardiac muscle cell action potential
GO:0086046 IMP membrane depolarization during SA node cell action potential
GO:0086063 IMP voltage-gated sodium channel activity involved in SA node cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:0097110 IPI scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000183873 SCN5A sodium channel, voltage-gated, type V, alpha subunit protein_coding Homo_sapiens

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