ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035206 Sppl2b 10090 + 10:80855275-80868705 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035597 Sppl2b-201 80855275-80868705 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000035597
Transcript ID C166 Tie2+ EC mES
ENSMUST00000035597 2.089±0.65 6.075±5.56 2.346±1.29

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001IB CIL_0001IB_0002 CGP
CIL_0003DX CIL_0003DX_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005765 ISS lysosomal membrane
GO:0005886 ISS plasma membrane
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0010008 ISS endosome membrane
GO:0030660 ISS Golgi-associated vesicle membrane
GO:0031293 ISS membrane protein intracellular domain proteolysis
GO:0042500 ISS aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 ISS protein homodimerization activity
GO:0050776 ISS regulation of immune response
GO:0071458 ISS integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 ISS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030448 sppl2 protein_coding Danio_rerio
ENSG00000005206 SPPL2B signal peptide peptidase like 2B protein_coding Homo_sapiens

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