ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040390 Map3k10 10090 - 7:27656375-27674598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036453 Map3k10-001 27656375-27674594 protein_coding
  ENSMUST00000108341 Map3k10-201 27656664-27674598 protein_coding
  ENSMUST00000133551 Map3k10-004 27664180-27674357 retained_intron
  ENSMUST00000138243 Map3k10-002 27668148-27674581 retained_intron
  ENSMUST00000152032 Map3k10-003 27664158-27665107 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000036453ENSMUST00000108341ENSMUST00000138243
Transcript ID C166 Tie2+ EC mES
ENSMUST00000036453 6.004±1.34 4.560±0.45 1.747±0.04
ENSMUST00000108341 2.684±0.57 0.695±0.00 N/A
ENSMUST00000138243 4.498±0.69 7.310±3.96 9.355±1.58

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0003714 IDA transcription corepressor activity
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0007224 IEA smoothened signaling pathway
GO:0008219 IEA cell death
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0018107 IEA peptidyl-threonine phosphorylation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043425 IEA bHLH transcription factor binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046330 IEA positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055672 map3k10 protein_coding Danio_rerio
ENSG00000130758 MAP3K10 mitogen-activated protein kinase kinase kinase 10 protein_coding Homo_sapiens

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