ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040663 Clcf1 10090 + 19:4214238-4223490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046506 Clcf1-001 4214238-4223490 protein_coding
  ENSMUST00000126457 Clcf1-004 4214594-4222513 processed_transcript
  ENSMUST00000132305 Clcf1-003 4214264-4223490 retained_intron
  ENSMUST00000138090 Clcf1-002 4214305-4223490 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000046506ENSMUST00000132305
Transcript ID C166 Tie2+ EC mES
ENSMUST00000046506 11.748±3.86 0.243±0.00 0.678±0.00
ENSMUST00000132305 6.833±3.34 0.224±0.20 0.297±0.08

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002639 IDA positive regulation of immunoglobulin production
GO:0002830 NAS positive regulation of type 2 immune response
GO:0005102 ISS receptor binding
GO:0005125 IDA cytokine activity
GO:0005127 ISS ciliary neurotrophic factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 ISS extracellular region
GO:0005622 TAS intracellular
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007259 IDA JAK-STAT cascade
GO:0008284 ISS positive regulation of cell proliferation
GO:0030183 IDA B cell differentiation
GO:0030890 IDA positive regulation of B cell proliferation
GO:0042517 IDA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0046982 ISS protein heterodimerization activity
GO:0048295 IDA positive regulation of isotype switching to IgE isotypes
GO:0048711 IDA positive regulation of astrocyte differentiation
GO:0050727 NAS regulation of inflammatory response
GO:0051466 TAS positive regulation of corticotropin-releasing hormone secretion
GO:0051896 TAS regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0070372 TAS regulation of ERK1 and ERK2 cascade
GO:0097058 IEA CRLF-CLCF1 complex
GO:0097059 IEA CNTFR-CLCF1 complex
GO:2000672 NAS negative regulation of motor neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076140 clcf1 protein_coding Danio_rerio
ENSG00000175505 CLCF1 cardiotrophin-like cytokine factor 1 protein_coding Homo_sapiens

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