ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041245 Wnk3 10090 + X:151198078-151320152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000096285 Wnk3-201 151198140-151318309 protein_coding
  ENSMUST00000131844 Wnk3-003 151207750-151226664 processed_transcript
  ENSMUST00000133852 Wnk3-001 151294520-151320152 processed_transcript
  ENSMUST00000149140 Wnk3-002 151198140-151315128 nonsense_mediated_decay
  ENSMUST00000184392 Wnk3-005 151198078-151315186 protein_coding
  ENSMUST00000184730 Wnk3-004 151198078-151315186 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECENSMUST00000133852ENSMUST00000184730
Transcript ID Tie2+ EC
ENSMUST00000133852 0.187±0.00
ENSMUST00000184730 1.374±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 ISS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005912 IDA adherens junction
GO:0005923 IDA tight junction
GO:0010765 ISS positive regulation of sodium ion transport
GO:0010800 ISS positive regulation of peptidyl-threonine phosphorylation
GO:0019869 IEA chloride channel inhibitor activity
GO:0032414 ISS positive regulation of ion transmembrane transporter activity
GO:0043066 IEA negative regulation of apoptotic process
GO:0046777 ISS protein autophosphorylation
GO:0051928 IEA positive regulation of calcium ion transport
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane
GO:2000021 IEA regulation of ion homeostasis
GO:2000651 ISS positive regulation of sodium ion transmembrane transporter activity
GO:2000682 ISS positive regulation of rubidium ion transport
GO:2000688 ISS positive regulation of rubidium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000196632 WNK3 WNK lysine deficient protein kinase 3 protein_coding Homo_sapiens

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