ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041301 Cftr 10090 + 6:18170687-18322768 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045706 Cftr-001 18170687-18322768 protein_coding
  ENSMUST00000115405 Cftr-004 18170687-18322767 nonsense_mediated_decay
  ENSMUST00000115406 Cftr-006 18170824-18321033 protein_coding
  ENSMUST00000129452 Cftr-002 18170771-18236655 protein_coding
  ENSMUST00000140407 Cftr-005 18170687-18322767 nonsense_mediated_decay
  ENSMUST00000140532 Cftr-003 18255224-18268130 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000045706ENSMUST00000115406
Transcript ID C166 Tie2+ EC mES
ENSMUST00000045706 0.177±0.07 0.042±0.02 0.022±0.01
ENSMUST00000115406 0.065±0.00 0.070±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00063R CIL_00063R_0003 CGP
CIL_0005U6 CIL_0005U6_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005254 ISS chloride channel activity
GO:0005260 IEA channel-conductance-controlling ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005769 ISS early endosome
GO:0005886 ISS plasma membrane
GO:0005902 IEA microvillus
GO:0006200 IEA ATP catabolic process
GO:0006695 IMP cholesterol biosynthetic process
GO:0006821 IGI chloride transport
GO:0006833 IEA water transport
GO:0009986 IEA cell surface
GO:0015106 IMP bicarbonate transmembrane transporter activity
GO:0015108 IMP chloride transmembrane transporter activity
GO:0015701 IEA bicarbonate transport
GO:0015705 IEA iodide transport
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019869 ISS chloride channel inhibitor activity
GO:0019899 IEA enzyme binding
GO:0030165 IEA PDZ domain binding
GO:0030301 IMP cholesterol transport
GO:0030321 IEA transepithelial chloride transport
GO:0030324 IEA lung development
GO:0030659 IEA cytoplasmic vesicle membrane
GO:0031205 IEA endoplasmic reticulum Sec complex
GO:0032870 IEA cellular response to hormone stimulus
GO:0034097 IEA response to cytokine
GO:0034707 IEA chloride channel complex
GO:0042311 IEA vasodilation
GO:0042493 IEA response to drug
GO:0043234 IEA protein complex
GO:0043434 IEA response to peptide hormone
GO:0043627 IEA response to estrogen
GO:0045909 IEA positive regulation of vasodilation
GO:0048240 IMP sperm capacitation
GO:0051454 IMP intracellular pH elevation
GO:0060081 IMP membrane hyperpolarization
GO:0070062 IEA extracellular vesicular exosome
GO:0071320 IDA cellular response to cAMP
GO:1902476 IEA chloride transmembrane transport
GO:1902943 IEA positive regulation of voltage-gated chloride channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041107 cftr protein_coding Danio_rerio
ENSG00000001626 CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) protein_coding Homo_sapiens

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