ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044813 Shb 10090 - 4:45423278-45532470 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061986 Shb-001 45423278-45530330 protein_coding
  ENSMUST00000125599 Shb-006 45447506-45489403 retained_intron
  ENSMUST00000130107 Shb-004 45444706-45492841 processed_transcript
  ENSMUST00000146236 Shb-005 45458129-45489794 protein_coding
  ENSMUST00000147448 Shb-003 45458320-45532470 protein_coding
  ENSMUST00000147926 Shb-002 45423278-45482802 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000061986
Transcript ID C166 Tie2+ EC mES
ENSMUST00000061986 25.917±2.58 5.964±3.57 2.350±0.89

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00081A CIL_00081A_0002 VISTA
CIL_0006TM CIL_0006TM_0002 CGP
CIL_0006TL CIL_0006TL_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001948 IDA glycoprotein binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005575 ND cellular_component
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006469 IMP negative regulation of protein kinase activity
GO:0006915 IEA apoptotic process
GO:0009967 TAS positive regulation of signal transduction
GO:0030097 IMP hemopoiesis
GO:0030154 IEA cell differentiation
GO:0042100 IDA B cell proliferation
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0048514 IGI blood vessel morphogenesis
GO:0071425 IMP hematopoietic stem cell proliferation
GO:1900194 IMP negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107338 SHB Src homology 2 domain containing adaptor protein B protein_coding Homo_sapiens
ENSG00000255872 RP11-613M10.9 protein_coding Homo_sapiens

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