ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000046207 Pik3r6 10090 + 11:68503019-68552698 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060441 Pik3r6-201 68503019-68552698 protein_coding
  ENSMUST00000102613 Pik3r6-001 68503019-68552698 protein_coding
  ENSMUST00000126069 Pik3r6-003 68536200-68544383 processed_transcript
  ENSMUST00000131669 Pik3r6-004 68552064-68552696 processed_transcript
  ENSMUST00000153671 Pik3r6-002 68503091-68552698 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000060441ENSMUST00000102613ENSMUST00000126069ENSMUST00000153671
Transcript ID C166 Tie2+ EC mES
ENSMUST00000060441 0.003±0.00 10.704±8.63 0.378±0.00
ENSMUST00000102613 0.002±0.00 3.365±1.78 N/A
ENSMUST00000126069 0.062±0.00 N/A N/A
ENSMUST00000153671 0.007±0.00 1.608±0.24 0.368±0.27

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00088C CIL_00088C_0002 VISTA
CIL_0009AZ CIL_0009AZ_0002 VISTA
CIL_00033Z CIL_00033Z_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005515 IEA protein binding
GO:0005944 IDA phosphatidylinositol 3-kinase complex, class IB
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0016020 IDA membrane
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0046854 IDA phosphatidylinositol phosphorylation
GO:0046934 IDA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046935 IDA 1-phosphatidylinositol-3-kinase regulator activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091140 pik3r6 protein_coding Danio_rerio
ENSG00000276231 PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Homo_sapiens

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