ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048154 Kmt2d 10090 - 15:98831669-98871204 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023741 Kmt2d-001 98831672-98871204 protein_coding
  ENSMUST00000178486 Kmt2d-201 98831669-98871183 protein_coding
  ENSMUST00000184363 Kmt2d-002 98854714-98856309 protein_coding
  ENSMUST00000191973 Kmt2d-003 98834301-98837121 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000023741ENSMUST00000178486
Transcript ID C166 Tie2+ EC mES
ENSMUST00000023741 5.667±1.73 2.800±2.71 1.998±1.22
ENSMUST00000178486 N/A 1.362±0.38 3.489±0.11

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00000J CIL_00000J_0002 CGP
CIL_00003S CIL_00003S_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001555 IMP oocyte growth
GO:0001701 IMP in utero embryonic development
GO:0005634 IEA nucleus
GO:0006342 IMP chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0033148 IEA positive regulation of intracellular estrogen receptor signaling pathway
GO:0035097 IEA histone methyltransferase complex
GO:0043627 IEA response to estrogen
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048477 IMP oogenesis
GO:0051568 IMP histone H3-K4 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037060 kmt2d protein_coding Danio_rerio
ENSG00000167548 KMT2D lysine (K)-specific methyltransferase 2D protein_coding Homo_sapiens

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