ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051331 Cacna1c 10090 - 6:118587240-119196418 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075591 Cacna1c-024 118592942-119108189 protein_coding
  ENSMUST00000078320 Cacna1c-004 118592464-119108189 protein_coding
  ENSMUST00000112790 Cacna1c-005 118592942-119108236 protein_coding
  ENSMUST00000112793 Cacna1c-010 118593892-119107975 protein_coding
  ENSMUST00000112825 Cacna1c-201 118592319-118757974 protein_coding
  ENSMUST00000185345 Cacna1c-019 118593793-119107975 protein_coding
  ENSMUST00000186889 Cacna1c-001 118587240-119196231 protein_coding
  ENSMUST00000187317 Cacna1c-018 118593793-119107975 protein_coding
  ENSMUST00000187386 Cacna1c-006 118593799-119080007 protein_coding
  ENSMUST00000187474 Cacna1c-008 118593647-119196387 protein_coding
  ENSMUST00000187849 Cacna1c-023 118614026-118627946 processed_transcript
  ENSMUST00000187940 Cacna1c-002 118593082-119196418 protein_coding
  ENSMUST00000188078 Cacna1c-015 118593793-119107975 protein_coding
  ENSMUST00000188106 Cacna1c-011 118593892-119107975 protein_coding
  ENSMUST00000188181 Cacna1c-012 118592319-118757974 processed_transcript
  ENSMUST00000188522 Cacna1c-014 118593647-119108573 protein_coding
  ENSMUST00000188865 Cacna1c-020 118593793-119107975 protein_coding
  ENSMUST00000189057 Cacna1c-003 118946163-119196409 processed_transcript
  ENSMUST00000189389 Cacna1c-016 118593793-119107975 protein_coding
  ENSMUST00000189520 Cacna1c-017 118593793-119107975 protein_coding
  ENSMUST00000189930 Cacna1c-013 118702217-118707147 retained_intron
  ENSMUST00000190285 Cacna1c-007 118593892-119196231 protein_coding
  ENSMUST00000191196 Cacna1c-021 118592304-118595426 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000075591ENSMUST00000078320ENSMUST00000112790ENSMUST00000112793ENSMUST00000186889ENSMUST00000187474ENSMUST00000187940ENSMUST00000188106ENSMUST00000188181ENSMUST00000188522ENSMUST00000191196
Transcript ID C166 Tie2+ EC mES
ENSMUST00000075591 0.393±0.15 N/A 0.034±0.00
ENSMUST00000078320 0.302±0.14 0.055±0.00 N/A
ENSMUST00000112790 0.411±0.19 0.071±0.00 N/A
ENSMUST00000112793 0.418±0.00 N/A N/A
ENSMUST00000186889 N/A N/A 0.020±0.00
ENSMUST00000187474 0.283±0.00 N/A 0.068±0.00
ENSMUST00000187940 N/A N/A 0.052±0.01
ENSMUST00000188106 0.547±0.00 N/A N/A
ENSMUST00000188181 0.251±0.05 0.064±0.00 N/A
ENSMUST00000188522 0.475±0.02 0.131±0.00 0.015±0.00
ENSMUST00000191196 N/A N/A 0.093±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002095 IDA caveolar macromolecular signaling complex
GO:0005245 TAS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005891 TAS voltage-gated calcium channel complex
GO:0006816 IMP calcium ion transport
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006939 IMP smooth muscle contraction
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007268 IMP synaptic transmission
GO:0007628 IGI adult walking behavior
GO:0008217 IMP regulation of blood pressure
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0008542 IMP visual learning
GO:0014069 IEA postsynaptic density
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0017156 IMP calcium ion-dependent exocytosis
GO:0019229 IMP regulation of vasoconstriction
GO:0019899 IPI enzyme binding
GO:0030018 IDA Z disc
GO:0030073 IMP insulin secretion
GO:0030252 IDA growth hormone secretion
GO:0030315 TAS T-tubule
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042593 IMP glucose homeostasis
GO:0043025 IDA neuronal cell body
GO:0043198 IDA dendritic shaft
GO:0046620 IMP regulation of organ growth
GO:0046872 IEA metal ion binding
GO:0051393 IEA alpha-actinin binding
GO:0060083 IMP smooth muscle contraction involved in micturition
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008398 cacna1c protein_coding Danio_rerio
ENSG00000151067 CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit protein_coding Homo_sapiens

Loading