ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057342 Sphk2 10090 - 7:45709467-45718002 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072836 Sphk2-002 45710285-45715207 protein_coding
  ENSMUST00000107737 Sphk2-001 45709467-45718002 protein_coding
  ENSMUST00000107738 Sphk2-003 45710267-45717902 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECENSMUST00000107737
Transcript ID Tie2+ EC
ENSMUST00000107737 3.768±0.72

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IGI blood vessel development
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005765 IEA lysosomal membrane
GO:0005829 IDA cytosol
GO:0006669 NAS sphinganine-1-phosphate biosynthetic process
GO:0006670 IMP sphingosine metabolic process
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007420 IGI brain development
GO:0008283 NAS cell proliferation
GO:0008284 IGI positive regulation of cell proliferation
GO:0008481 NAS sphinganine kinase activity
GO:0016020 IDA membrane
GO:0017050 IDA D-erythro-sphingosine kinase activity
GO:0043066 NAS negative regulation of apoptotic process
GO:0046834 IEA lipid phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069893 sphk2 protein_coding Danio_rerio
ENSG00000063176 SPHK2 sphingosine kinase 2 protein_coding Homo_sapiens

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