ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000066551 Hmgb1 10090 - 5:149046702-149184489 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085546 Hmgb1-001 149046702-149053040 protein_coding
  ENSMUST00000093196 Hmgb1-002 149048645-149051616 protein_coding
  ENSMUST00000110505 Hmgb1-003 149048228-149051300 protein_coding
  ENSMUST00000123645 Hmgb1-005 149050373-149052981 retained_intron
  ENSMUST00000125605 Hmgb1-008 149050315-149053513 protein_coding
  ENSMUST00000133667 Hmgb1-004 149050068-149053016 retained_intron
  ENSMUST00000138553 Hmgb1-007 149049824-149052377 protein_coding
  ENSMUST00000139443 Hmgb1-006 149049401-149053011 protein_coding
  ENSMUST00000155086 Hmgb1-009 149049153-149050447 retained_intron
  ENSMUST00000202133 Hmgb1-010 149048793-149184489 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000085546ENSMUST00000110505ENSMUST00000133667ENSMUST00000202133
Transcript ID C166 Tie2+ EC mES
ENSMUST00000085546 50.845±10.28 36.467±19.69 24.239±10.64
ENSMUST00000110505 46.233±13.29 N/A N/A
ENSMUST00000133667 95.545±21.90 N/A N/A
ENSMUST00000202133 142.295±32.97 111.106±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007UA CIL_0007UA_0002 VISTA
CIL_0004CF CIL_0004CF_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000793 IEA condensed chromosome
GO:0001786 TAS phosphatidylserine binding
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006288 IEA base-excision repair, DNA ligation
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006954 TAS inflammatory response
GO:0008134 IEA transcription factor binding
GO:0008201 IEA heparin binding
GO:0009986 IEA cell surface
GO:0017053 IEA transcriptional repressor complex
GO:0017055 IEA negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0033151 IEA V(D)J recombination
GO:0043065 IEA positive regulation of apoptotic process
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043388 IEA positive regulation of DNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070491 IEA repressing transcription factor binding
GO:2000426 IDA negative regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030479 hmgb1b protein_coding Danio_rerio
ENSG00000189403 HMGB1 high mobility group box 1 protein_coding Homo_sapiens

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