ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068798 Rap1a 10090 - 3:105727267-105801336 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090678 Rap1a-001 105727267-105801336 protein_coding
  ENSMUST00000197094 Rap1a-004 105728643-105801285 protein_coding
  ENSMUST00000198004 Rap1a-003 105737896-105801310 protein_coding
  ENSMUST00000199969 Rap1a-002 105728314-105750328 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000090678ENSMUST00000197094ENSMUST00000198004ENSMUST00000199969
Transcript ID C166 Tie2+ EC mES
ENSMUST00000090678 7.684±1.08 10.954±7.22 16.838±5.33
ENSMUST00000197094 18.969±2.38 33.572±1.09 N/A
ENSMUST00000198004 N/A 55.170±28.66 N/A
ENSMUST00000199969 22.605±1.89 15.403±3.19 7.547±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005737 ISS cytoplasm
GO:0005769 ISS early endosome
GO:0005770 ISS late endosome
GO:0005886 IEA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007264 IDA small GTPase mediated signal transduction
GO:0008565 ISS protein transporter activity
GO:0010976 ISS positive regulation of neuron projection development
GO:0015031 ISS protein transport
GO:0017016 IPI Ras GTPase binding
GO:0017034 ISS Rap guanyl-nucleotide exchange factor activity
GO:0030054 IDA cell junction
GO:0032045 IDA guanyl-nucleotide exchange factor complex
GO:0032403 ISS protein complex binding
GO:0032486 ISS Rap protein signal transduction
GO:0032854 ISS positive regulation of Rap GTPase activity
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043005 IDA neuron projection
GO:0045860 ISS positive regulation of protein kinase activity
GO:0048471 ISS perinuclear region of cytoplasm
GO:0061028 ISS establishment of endothelial barrier
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0071320 ISS cellular response to cAMP
GO:1901888 ISS regulation of cell junction assembly
GO:1990090 ISS cellular response to nerve growth factor stimulus
GO:2000301 IGI negative regulation of synaptic vesicle exocytosis
GO:2001214 IMP positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000116473 RAP1A RAP1A, member of RAS oncogene family protein_coding Homo_sapiens

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