ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000078817 Nlrp12 10090 - 7:3221510-3249740 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000108653 Nlrp12-201 3221510-3249740 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECENSMUST00000108653
Transcript ID C166 Tie2+ EC
ENSMUST00000108653 0.009±0.00 0.019±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004ML CIL_0004ML_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0008588 IEA release of cytoplasmic sequestered NF-kappaB
GO:0009968 IEA negative regulation of signal transduction
GO:0031953 IEA negative regulation of protein autophosphorylation
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0036336 IMP dendritic cell migration
GO:0043122 IEA regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043281 IEA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045345 IEA positive regulation of MHC class I biosynthetic process
GO:0045409 IEA negative regulation of interleukin-6 biosynthetic process
GO:0045751 IEA negative regulation of Toll signaling pathway
GO:0050710 IEA negative regulation of cytokine secretion
GO:0050711 IEA negative regulation of interleukin-1 secretion
GO:0050728 IEA negative regulation of inflammatory response
GO:0070373 IMP negative regulation of ERK1 and ERK2 cascade
GO:0071345 IMP cellular response to cytokine stimulus
GO:1901223 IMP negative regulation of NIK/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000142405 NLRP12 NLR family, pyrin domain containing 12 protein_coding Homo_sapiens

Loading