ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: IMP (inosine 5'-monophosphate) dehydrogenase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000326739 IMPDH2-001 ENSG00000178035 9606 - 3:49024325-49029390 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000326739
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000326739 80.609±23.83 155.955±53.10 11.550±0.00 73.318±0.00 64.285±37.45

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IDA nucleotide binding
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0003824 IEA catalytic activity
GO:0003938 IEA IMP dehydrogenase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005778 IDA peroxisomal membrane
GO:0005829 TAS cytosol
GO:0006051 IEA N-acetylmannosamine metabolic process
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006177 IEA GMP biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0018580 IEA nitronate monooxygenase activity
GO:0030554 IEA adenyl nucleotide binding
GO:0044281 TAS small molecule metabolic process
GO:0046651 IEA lymphocyte proliferation
GO:0046872 IEA metal ion binding
GO:0047465 IEA N-acylglucosamine-6-phosphate 2-epimerase activity
GO:0051289 IEA protein homotetramerization
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0060041 IEA retina development in camera-type eye
GO:0070062 IDA extracellular vesicular exosome
GO:0071353 IEA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000081111 Impdh2-001 protein_coding Mus_musculus 0 2039
ENSMUST00000120826 Gm15210-001 processed_pseudogene Mus_musculus 0 2001
ENSMUST00000194904 Impdh2-002 protein_coding Mus_musculus 0 660
ENSMUST00000193421 Impdh2-005 protein_coding Mus_musculus 0 647
ENSMUST00000194365 Impdh2-008 retained_intron Mus_musculus 0 370
ENSMUST00000195456 Impdh2-007 retained_intron Mus_musculus 3e-20 104

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