Transcript ID | HAoEC | HUVEC |
---|---|---|
ENST00000394597 | 2.343±0.51 | 4.121±0.64 |
Transcript Info |
||||||
Description: | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | |||||
---|---|---|---|---|---|---|
Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000394597 ![]() |
RFFL-004 |
ENSG00000092871 ![]() |
9606 | - |
17:35009118-35063852 |
protein_coding |
Expression Patterns
|
Conserved Regions |
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Not located within a conserved region. |
Gene Ontology | ||
---|---|---|
GO ID | Evidence Type | GO Description |
GO:0002020 | IPI | protease binding |
GO:0002039 | IPI | p53 binding |
GO:0002947 | IDA | tumor necrosis factor receptor superfamily complex |
GO:0005515 | IPI:IEA | protein binding |
GO:0005737 | IDA | cytoplasm |
GO:0005886 | IDA | plasma membrane |
GO:0006511 | IDA | ubiquitin-dependent protein catabolic process |
GO:0008270 | IEA | zinc ion binding |
GO:0010008 | IDA | endosome membrane |
GO:0010762 | ISS | regulation of fibroblast migration |
GO:0010804 | IMP | negative regulation of tumor necrosis factor-mediated signaling pathway |
GO:0016020 | IDA | membrane |
GO:0016874 | IEA | ligase activity |
GO:0019901 | IPI | protein kinase binding |
GO:0031625 | IPI | ubiquitin protein ligase binding |
GO:0032006 | IC | regulation of TOR signaling |
GO:0042787 | IMP | protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
GO:0043161 | IMP | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO:0061630 | IDA | ubiquitin protein ligase activity |
GO:0070936 | IDA | protein K48-linked ubiquitination |
GO:1901797 | IMP | negative regulation of signal transduction by p53 class mediator |
GO:1902042 | IMP | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
GO:2001271 | IMP | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000071152
![]() |
Rffl-201 | protein_coding | Mus_musculus | 0 | 1555 |
ENSMUST00000074515
![]() |
Rffl-001 | protein_coding | Mus_musculus | 0 | 1447 |
ENSMUST00000108173
![]() |
Rffl-203 | protein_coding | Mus_musculus | 0 | 1445 |
ENSMUST00000093975
![]() |
Rffl-202 | protein_coding | Mus_musculus | 0 | 1439 |
ENSMUST00000103218
![]() |
Rffl-002 | protein_coding | Mus_musculus | 0 | 726 |
ENSMUST00000021036
![]() |
Rffl-003 | protein_coding | Mus_musculus | 0 | 726 |
ENSMUST00000126660
![]() |
Rffl-004 | protein_coding | Mus_musculus | 0 | 616 |
ENSDART00000065132
![]() |
RFFL (2 of 2)-001 | protein_coding | Danio_rerio | 0 | 217 |
ENSMUST00000021039
![]() |
Lig3-201 | protein_coding | Mus_musculus | 2.94273e-44 | 185 |
ENSMUST00000173722
![]() |
Lig3-009 | protein_coding | Mus_musculus | 2.94273e-44 | 185 |