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Transcript Info |
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Description: | major histocompatibility complex, class II, DR beta 1 | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000419393 ![]() |
HLA-DRB1-001 |
ENSG00000228080 ![]() |
9606 | - |
CHR_HSCHR6_MHC_SSTO_CTG1:32670593-32685299 |
protein_coding |
Genome Exciting message Features Connecting Powered by Dalliance 0.11.11 |
Expression PatternsNo expression data. |
Conserved Regions |
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Not located within a conserved region. |
Gene Ontology | ||
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GO ID | Evidence Type | GO Description |
GO:0000139 | TAS | Golgi membrane |
GO:0002381 | ISS | immunoglobulin production involved in immunoglobulin mediated immune response |
GO:0002437 | IDA | inflammatory response to antigenic stimulus |
GO:0002455 | ISS | humoral immune response mediated by circulating immunoglobulin |
GO:0002503 | IDA | peptide antigen assembly with MHC class II protein complex |
GO:0002862 | IDA | negative regulation of inflammatory response to antigenic stimulus |
GO:0005515 | IPI:IEA | protein binding |
GO:0005765 | IDA | lysosomal membrane |
GO:0005886 | TAS | plasma membrane |
GO:0005887 | TAS | integral component of plasma membrane |
GO:0006955 | ISS:IEA | immune response |
GO:0007165 | NAS | signal transduction |
GO:0009897 | ISS | external side of plasma membrane |
GO:0012507 | TAS | ER to Golgi transport vesicle membrane |
GO:0016020 | IEA | membrane |
GO:0016045 | ISS | detection of bacterium |
GO:0019221 | TAS | cytokine-mediated signaling pathway |
GO:0019882 | IEA | antigen processing and presentation |
GO:0019886 | TAS | antigen processing and presentation of exogenous peptide antigen via MHC class II |
GO:0030658 | TAS | transport vesicle membrane |
GO:0030666 | TAS | endocytic vesicle membrane |
GO:0030669 | TAS | clathrin-coated endocytic vesicle membrane |
GO:0031295 | TAS | T cell costimulation |
GO:0031902 | IDA | late endosome membrane |
GO:0032395 | TAS | MHC class II receptor activity |
GO:0032588 | TAS | trans-Golgi network membrane |
GO:0032673 | ISS | regulation of interleukin-4 production |
GO:0032689 | ISS | negative regulation of interferon-gamma production |
GO:0035774 | ISS | positive regulation of insulin secretion involved in cellular response to glucose stimulus |
GO:0042088 | ISS | T-helper 1 type immune response |
GO:0042130 | ISS | negative regulation of T cell proliferation |
GO:0042605 | ISS | peptide antigen binding |
GO:0042613 | IEA:IDA | MHC class II protein complex |
GO:0050852 | TAS | T cell receptor signaling pathway |
GO:0051262 | ISS | protein tetramerization |
GO:0060333 | TAS | interferon-gamma-mediated signaling pathway |
GO:0071556 | TAS | integral component of lumenal side of endoplasmic reticulum membrane |
GO:2001179 | ISS | regulation of interleukin-10 secretion |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000074557
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H2-Eb1-001 | protein_coding | Mus_musculus | 0 | 706 |