ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: calpain 1, (mu/I) large subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000014216 CAPN1 9606 + 11:65180566-65212006 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000279247 CAPN1-003 65181872-65212005 protein_coding
  ENST00000524773 CAPN1-002 65181745-65212001 protein_coding
  ENST00000525013 CAPN1-023 65206257-65209383 retained_intron
  ENST00000526468 CAPN1-015 65183336-65188000 protein_coding
  ENST00000526954 CAPN1-021 65182000-65188019 nonsense_mediated_decay
  ENST00000526966 CAPN1-017 65181723-65185945 protein_coding
  ENST00000527189 CAPN1-019 65181931-65186004 processed_transcript
  ENST00000527323 CAPN1-004 65182462-65211987 protein_coding
  ENST00000527469 CAPN1-020 65181934-65185937 processed_transcript
  ENST00000527699 CAPN1-013 65182435-65183592 protein_coding
  ENST00000527739 CAPN1-009 65181687-65185945 protein_coding
  ENST00000527887 CAPN1-016 65188245-65188689 retained_intron
  ENST00000527897 CAPN1-006 65185932-65187686 retained_intron
  ENST00000528165 CAPN1-007 65208478-65212005 retained_intron
  ENST00000528396 CAPN1-026 65180566-65185950 protein_coding
  ENST00000528739 CAPN1-032 65181919-65183582 processed_transcript
  ENST00000529133 CAPN1-027 65181037-65186033 protein_coding
  ENST00000530442 CAPN1-014 65181800-65183668 retained_intron
  ENST00000530495 CAPN1-025 65203372-65206669 processed_transcript
  ENST00000530567 CAPN1-008 65209144-65212006 retained_intron
  ENST00000531068 CAPN1-012 65182435-65183503 protein_coding
  ENST00000532285 CAPN1-011 65181931-65182890 protein_coding
  ENST00000533079 CAPN1-022 65187941-65206075 retained_intron
  ENST00000533129 CAPN1-028 65181733-65211858 protein_coding
  ENST00000533704 CAPN1-024 65208950-65210392 retained_intron
  ENST00000533820 CAPN1-001 65181194-65212006 protein_coding
  ENST00000533909 CAPN1-029 65182453-65183581 protein_coding
  ENST00000534373 CAPN1-010 65181938-65183543 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000279247ENST00000524773ENST00000527469ENST00000530567ENST00000533129ENST00000533820
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000279247 12.801±0.05 31.846±12.37 N/A 23.631±0.00 51.317±63.85
ENST00000524773 N/A N/A N/A 10.345±0.00 8.447±0.00
ENST00000527469 N/A 27.635±0.00 N/A N/A 47.353±0.00
ENST00000530567 78.565±30.34 N/A 37.274±0.00 N/A N/A
ENST00000533129 17.215±6.10 26.587±14.42 N/A 26.616±0.00 10.228±7.80
ENST00000533820 N/A N/A N/A N/A 0.588±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004198 IEA:ISS calcium-dependent cysteine-type endopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006508 IEA:ISS proteolysis
GO:0008284 TAS positive regulation of cell proliferation
GO:0016020 IDA membrane
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0032801 IEA receptor catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045199 CAPN1 (1 of 2) protein_coding Danio_rerio
ENSDARG00000055338 CAPN1 (2 of 2) protein_coding Danio_rerio
ENSMUSG00000024942 Capn1 protein_coding Mus_musculus

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