ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: runt-related transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000020633 RUNX3 9606 - 1:24899511-24965121 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308873 RUNX3-001 24899518-24929877 protein_coding
  ENST00000338888 RUNX3-002 24901029-24964984 protein_coding
  ENST00000399916 RUNX3-201 24899511-24965010 protein_coding
  ENST00000479341 RUNX3-003 24929737-24965121 processed_transcript
  ENST00000496967 RUNX3-004 24902572-24928798 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000308873ENST00000338888
Transcript ID HAoEC HUVEC
ENST00000308873 0.828±0.54 0.013±0.01
ENST00000338888 0.018±0.01 0.013±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007ZX CIL_0007ZX_0001 VISTA

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000790 ISS nuclear chromatin
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981 ISS sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0002062 IEA chondrocyte differentiation
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 NAS ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0007411 IEA axon guidance
GO:0031069 IEA hair follicle morphogenesis
GO:0031175 IEA neuron projection development
GO:0032609 IEA interferon-gamma production
GO:0045786 ISS negative regulation of cell cycle
GO:0048469 IEA cell maturation
GO:0048935 TAS peripheral nervous system neuron development
GO:0050680 ISS negative regulation of epithelial cell proliferation
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052826 runx3 protein_coding Danio_rerio
ENSMUSG00000070691 Runx3 protein_coding Mus_musculus

Loading