ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070691 Runx3 10090 + 4:135120652-135177990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056977 Runx3-001 135120652-135177990 protein_coding
  ENSMUST00000119564 Runx3-002 135152496-135176181 protein_coding
  ENSMUST00000127109 Runx3-006 135154436-135155342 processed_transcript
  ENSMUST00000137027 Runx3-004 135153160-135155371 processed_transcript
  ENSMUST00000140642 Runx3-005 135153505-135155426 processed_transcript
  ENSMUST00000156478 Runx3-003 135152938-135155609 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000056977ENSMUST00000119564
Transcript ID C166 Tie2+ EC mES
ENSMUST00000056977 N/A 0.018±0.00 0.153±0.01
ENSMUST00000119564 0.123±0.00 0.037±0.01 0.271±0.16

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007ZX CIL_0007ZX_0002 VISTA

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0002062 IGI chondrocyte differentiation
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007411 IMP axon guidance
GO:0031069 IMP hair follicle morphogenesis
GO:0031175 IMP neuron projection development
GO:0032609 IDA interferon-gamma production
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0045786 IMP negative regulation of cell cycle
GO:0048469 IGI cell maturation
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052826 runx3 protein_coding Danio_rerio
ENSG00000020633 RUNX3 runt-related transcription factor 3 protein_coding Homo_sapiens

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