ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000023228 NDUFS1 9606 - 2:206114817-206159603 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233190 NDUFS1-001 206114817-206159603 protein_coding
  ENST00000423725 NDUFS1-005 206123819-206159509 protein_coding
  ENST00000432169 NDUFS1-002 206124101-206159425 protein_coding
  ENST00000440274 NDUFS1-003 206123956-206159425 protein_coding
  ENST00000449699 NDUFS1-007 206124101-206159194 protein_coding
  ENST00000454195 NDUFS1-008 206147782-206159257 protein_coding
  ENST00000455934 NDUFS1-201 206123111-206159194 protein_coding
  ENST00000456284 NDUFS1-009 206147646-206159425 nonsense_mediated_decay
  ENST00000457011 NDUFS1-004 206123945-206159425 protein_coding
  ENST00000498520 NDUFS1-010 206127560-206132969 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000233190ENST00000423725ENST00000449699ENST00000455934
Transcript ID HAoEC HUVEC
ENST00000233190 3.419±0.10 3.426±1.88
ENST00000423725 28.076±0.25 21.608±2.81
ENST00000449699 22.692±6.74 12.415±10.11
ENST00000455934 11.690±0.21 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00039O CIL_00039O_0001 CGP
CIL_0001R4 CIL_0001R4_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005747 IDA mitochondrial respiratory chain complex I
GO:0005758 IDA mitochondrial intermembrane space
GO:0006120 NAS mitochondrial electron transport, NADH to ubiquinone
GO:0008137 IEA:NAS NADH dehydrogenase (ubiquinone) activity
GO:0008637 IDA apoptotic mitochondrial changes
GO:0009055 IEA:NAS electron carrier activity
GO:0016020 IEA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0022904 TAS respiratory electron transport chain
GO:0042773 IEA ATP synthesis coupled electron transport
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045333 IMP cellular respiration
GO:0046034 IMP ATP metabolic process
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0055114 IEA oxidation-reduction process
GO:0072593 IMP reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028546 ndufs1 protein_coding Danio_rerio
ENSMUSG00000025968 Ndufs1 protein_coding Mus_musculus

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