ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: macrophage scavenger receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000038945 MSR1 9606 - 8:16107878-16567490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262101 MSR1-001 16109431-16192715 protein_coding
  ENST00000350896 MSR1-201 16107878-16192791 protein_coding
  ENST00000355282 MSR1-002 16110085-16177988 protein_coding
  ENST00000381998 MSR1-003 16139319-16192659 protein_coding
  ENST00000445506 MSR1-004 16110046-16186272 protein_coding
  ENST00000517522 MSR1-013 16368086-16383328 processed_transcript
  ENST00000518026 MSR1-007 16175263-16567362 protein_coding
  ENST00000518343 MSR1-010 16256331-16567420 processed_transcript
  ENST00000518960 MSR1-008 16175210-16215074 protein_coding
  ENST00000519060 MSR1-005 16140655-16192651 nonsense_mediated_decay
  ENST00000520846 MSR1-012 16467752-16495880 processed_transcript
  ENST00000521876 MSR1-011 16250398-16511916 processed_transcript
  ENST00000522130 MSR1-009 16467764-16567490 processed_transcript
  ENST00000522672 MSR1-006 16120889-16164251 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000350896ENST00000381998ENST00000445506ENST00000517522ENST00000518026ENST00000518343ENST00000518960ENST00000519060ENST00000520846ENST00000521876ENST00000522130ENST00000522672
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000350896 0.122±0.00 N/A N/A N/A 0.048±0.04
ENST00000381998 N/A 0.043±0.01 1.953±0.00 N/A 0.048±0.00
ENST00000445506 N/A N/A N/A N/A 0.085±0.00
ENST00000517522 4.177±0.00 N/A N/A 0.653±0.00 1.469±0.51
ENST00000518026 N/A N/A N/A 0.460±0.00 N/A
ENST00000518343 0.687±0.46 0.166±0.04 N/A 0.385±0.00 1.124±1.05
ENST00000518960 N/A 0.435±0.12 N/A N/A N/A
ENST00000519060 N/A N/A N/A N/A 0.084±0.00
ENST00000520846 N/A N/A N/A 1.553±0.00 0.797±0.63
ENST00000521876 N/A 0.891±0.54 N/A N/A 0.151±0.00
ENST00000522130 N/A N/A N/A 1.095±0.00 0.733±0.62
ENST00000522672 N/A N/A N/A 0.219±0.00 0.041±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000456 CIL_000456_0001 CGP
CIL_0001VY CIL_0001VY_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IPI protein binding
GO:0005581 IEA collagen trimer
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006898 IEA receptor-mediated endocytosis
GO:0007165 IEA signal transduction
GO:0010744 ISS positive regulation of macrophage derived foam cell differentiation
GO:0010886 ISS positive regulation of cholesterol storage
GO:0016020 IEA membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 ISS cholesterol transport
GO:0030666 TAS endocytic vesicle membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0034362 IEA low-density lipoprotein particle
GO:0034381 ISS plasma lipoprotein particle clearance
GO:0042953 IEA lipoprotein transport
GO:0071407 IEA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000025044 Msr1 protein_coding Mus_musculus

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