ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: LIM domain and actin binding 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000050405 LIMA1 9606 - 12:50175788-50283546 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341247 LIMA1-003 50175788-50283546 protein_coding
  ENST00000394943 LIMA1-001 50175788-50283506 protein_coding
  ENST00000547825 LIMA1-007 50175788-50202112 protein_coding
  ENST00000549064 LIMA1-014 50177698-50182179 retained_intron
  ENST00000550592 LIMA1-008 50222318-50249893 protein_coding
  ENST00000550611 LIMA1-010 50222167-50224481 processed_transcript
  ENST00000551486 LIMA1-012 50204344-50222165 retained_intron
  ENST00000551691 LIMA1-009 50222260-50283484 protein_coding
  ENST00000552008 LIMA1-011 50192452-50220556 processed_transcript
  ENST00000552045 LIMA1-016 50195618-50200892 retained_intron
  ENST00000552338 LIMA1-015 50177774-50196047 processed_transcript
  ENST00000552491 LIMA1-017 50175788-50200847 protein_coding
  ENST00000552720 LIMA1-005 50177006-50283456 nonsense_mediated_decay
  ENST00000552783 LIMA1-002 50175790-50222705 protein_coding
  ENST00000552823 LIMA1-006 50175788-50222348 protein_coding
  ENST00000552909 LIMA1-004 50176885-50222356 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000341247ENST00000547825ENST00000551486ENST00000552491ENST00000552783ENST00000552823ENST00000552909
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000341247 N/A 18.041±8.63 N/A N/A 4.090±2.61
ENST00000547825 N/A N/A N/A N/A 1.914±0.66
ENST00000551486 N/A N/A N/A N/A 4.404±0.63
ENST00000552491 8.098±0.00 14.396±4.37 17.680±0.00 N/A 7.868±3.38
ENST00000552783 N/A 18.251±4.24 N/A 25.914±0.00 10.718±6.77
ENST00000552823 N/A 8.841±4.84 N/A N/A 5.978±2.21
ENST00000552909 N/A 6.606±0.00 N/A N/A 3.593±2.34

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008PE CIL_0008PE_0001 VISTA
CIL_0008CC CIL_0008CC_0001 VISTA
CIL_0000LJ CIL_0000LJ_0001 CGP
CIL_00051T CIL_00051T_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IDA stress fiber
GO:0003785 IDA actin monomer binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0008270 IEA zinc ion binding
GO:0015629 IDA actin cytoskeleton
GO:0030835 IEA:IDA negative regulation of actin filament depolymerization
GO:0031529 IDA ruffle organization
GO:0051015 IEA:IDA actin filament binding
GO:0051017 IEA:IDA actin filament bundle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000023022 Lima1 protein_coding Mus_musculus

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