ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: potassium voltage-gated channel, subfamily H (eag-related), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000055118 KCNH2 9606 - 7:150944961-150978315 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262186 KCNH2-001 150944961-150978315 protein_coding
  ENST00000330883 KCNH2-004 150944961-150955906 protein_coding
  ENST00000430723 KCNH2-201 150949899-150978100 protein_coding
  ENST00000461280 KCNH2-008 150949423-150955810 retained_intron
  ENST00000473610 KCNH2-005 150949416-150955828 retained_intron
  ENST00000532957 KCNH2-002 150949415-150978136 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000262186ENST00000330883ENST00000430723ENST00000461280ENST00000473610ENST00000532957
Transcript ID HAoEC HUVEC
ENST00000262186 1.217±0.00 0.011±0.00
ENST00000330883 N/A 0.057±0.06
ENST00000430723 0.017±0.00 0.046±0.03
ENST00000461280 1.503±0.28 0.082±0.13
ENST00000473610 0.024±0.00 0.034±0.00
ENST00000532957 1.486±1.26 0.024±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008T1 CIL_0008T1_0001 VISTA
CIL_0004OG CIL_0004OG_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000155 IEA phosphorelay sensor kinase activity
GO:0000160 IEA phosphorelay signal transduction system
GO:0003064 TAS regulation of heart rate by hormone
GO:0004871 IEA signal transducer activity
GO:0005216 IEA ion channel activity
GO:0005242 IDA inward rectifier potassium channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005251 IDA delayed rectifier potassium channel activity
GO:0005515 IPI:IEA protein binding
GO:0005635 IEA nuclear envelope
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006811 IEA ion transport
GO:0007165 IEA signal transduction
GO:0007268 TAS synaptic transmission
GO:0008076 IDA voltage-gated potassium channel complex
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0023014 IEA signal transduction by phosphorylation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035690 IDA cellular response to drug
GO:0042391 IDA regulation of membrane potential
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0055075 IDA potassium ion homeostasis
GO:0055085 IEA transmembrane transport
GO:0060048 IMP cardiac muscle contraction
GO:0060306 IDA regulation of membrane repolarization
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071435 IDA potassium ion export
GO:0071805 IDA potassium ion transmembrane transport
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086010 IDA membrane depolarization during action potential
GO:0086011 IDA membrane repolarization during action potential
GO:0086013 IMP membrane repolarization during cardiac muscle cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901379 IDA regulation of potassium ion transmembrane transport
GO:1901380 IDA negative regulation of potassium ion transmembrane transport
GO:1901381 IDA positive regulation of potassium ion transmembrane transport
GO:1902282 IMP voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1902303 IDA negative regulation of potassium ion export

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029881 kcnh2a protein_coding Danio_rerio
ENSDARG00000060053 KCNH2 (2 of 2) protein_coding Danio_rerio
ENSMUSG00000038319 Kcnh2 protein_coding Mus_musculus

Loading