ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038319 Kcnh2 10090 - 5:24319589-24351604 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036092 Kcnh2-001 24319589-24351604 protein_coding
  ENSMUST00000115098 Kcnh2-002 24319589-24329591 protein_coding
  ENSMUST00000126791 Kcnh2-003 24324490-24325789 processed_transcript
  ENSMUST00000129246 Kcnh2-005 24320083-24322254 processed_transcript
  ENSMUST00000142197 Kcnh2-004 24325448-24326519 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000036092ENSMUST00000115098ENSMUST00000142197
Transcript ID C166 Tie2+ EC mES
ENSMUST00000036092 7.310±2.14 0.209±0.22 0.621±0.32
ENSMUST00000115098 36.132±11.22 0.006±0.00 1.235±0.00
ENSMUST00000142197 N/A 0.047±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008T1 CIL_0008T1_0002 VISTA
CIL_0004OG CIL_0004OG_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000155 IEA phosphorelay sensor kinase activity
GO:0000160 IEA phosphorelay signal transduction system
GO:0005242 IDA inward rectifier potassium channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005251 IEA delayed rectifier potassium channel activity
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0008076 IEA voltage-gated potassium channel complex
GO:0009986 IEA cell surface
GO:0023014 IEA signal transduction by phosphorylation
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035690 IEA cellular response to drug
GO:0042391 IDA regulation of membrane potential
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0055075 IEA potassium ion homeostasis
GO:0060048 IEA cardiac muscle contraction
GO:0060306 IEA regulation of membrane repolarization
GO:0060307 IDA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071435 IEA potassium ion export
GO:0071805 IDA potassium ion transmembrane transport
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086010 IEA membrane depolarization during action potential
GO:0086011 IEA membrane repolarization during action potential
GO:0086013 IEA membrane repolarization during cardiac muscle cell action potential
GO:0086091 IDA regulation of heart rate by cardiac conduction
GO:1901379 IEA regulation of potassium ion transmembrane transport
GO:1901380 IEA negative regulation of potassium ion transmembrane transport
GO:1901381 IEA positive regulation of potassium ion transmembrane transport
GO:1902282 IEA voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1902303 IEA negative regulation of potassium ion export

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029881 kcnh2a protein_coding Danio_rerio
ENSDARG00000060053 KCNH2 (2 of 2) protein_coding Danio_rerio
ENSG00000055118 KCNH2 potassium voltage-gated channel, subfamily H (eag-related), member 2 protein_coding Homo_sapiens

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