ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: thromboxane A synthase 1 (platelet)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000059377 TBXAS1 9606 + 7:139777051-140020325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263552 TBXAS1-201 139778248-140020323 protein_coding
  ENST00000336425 TBXAS1-001 139778400-140020293 protein_coding
  ENST00000411653 TBXAS1-005 139829264-140020325 protein_coding
  ENST00000414041 TBXAS1-013 139829302-139936235 nonsense_mediated_decay
  ENST00000414508 TBXAS1-202 139829153-140020323 protein_coding
  ENST00000416849 TBXAS1-203 139778248-140020323 protein_coding
  ENST00000422328 TBXAS1-006 139829247-140020291 nonsense_mediated_decay
  ENST00000425687 TBXAS1-002 139778248-140020289 protein_coding
  ENST00000438104 TBXAS1-011 139778338-139936307 protein_coding
  ENST00000448866 TBXAS1-003 139829224-140020293 protein_coding
  ENST00000455353 TBXAS1-008 139829254-139914029 protein_coding
  ENST00000458722 TBXAS1-004 139829254-140020279 protein_coding
  ENST00000462053 TBXAS1-016 139777147-139797484 processed_transcript
  ENST00000462275 TBXAS1-007 139829273-140016829 processed_transcript
  ENST00000469630 TBXAS1-015 139953435-139963051 retained_intron
  ENST00000473948 TBXAS1-018 139778136-139782729 processed_transcript
  ENST00000474763 TBXAS1-017 139778254-139797484 processed_transcript
  ENST00000476637 TBXAS1-014 139829271-139953517 retained_intron
  ENST00000481440 TBXAS1-010 139778256-139797483 processed_transcript
  ENST00000492560 TBXAS1-012 139829249-139875892 retained_intron
  ENST00000493340 TBXAS1-009 139777051-139789622 processed_transcript
  ENST00000494876 TBXAS1-019 139957581-139962236 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000263552ENST00000336425ENST00000411653ENST00000414041ENST00000414508ENST00000422328ENST00000425687ENST00000438104ENST00000448866ENST00000455353ENST00000458722ENST00000462053ENST00000462275ENST00000469630ENST00000474763ENST00000476637ENST00000481440ENST00000492560ENST00000493340ENST00000494876
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000263552 N/A N/A N/A N/A 0.037±0.00
ENST00000336425 N/A 0.555±0.15 1.497±0.00 N/A 0.202±0.05
ENST00000411653 N/A 1.169±0.56 N/A N/A 0.078±0.00
ENST00000414041 N/A 1.344±0.00 N/A N/A 0.153±0.00
ENST00000414508 N/A N/A N/A N/A 0.249±0.11
ENST00000422328 N/A 0.441±0.00 N/A N/A 0.051±0.00
ENST00000425687 0.515±0.00 0.305±0.00 N/A N/A 0.504±0.00
ENST00000438104 N/A N/A N/A N/A 0.477±0.00
ENST00000448866 N/A 1.196±0.65 3.036±0.00 N/A 0.324±0.19
ENST00000455353 N/A N/A N/A 0.109±0.00 0.140±0.02
ENST00000458722 N/A N/A N/A N/A 0.569±0.00
ENST00000462053 1.087±0.00 N/A 9.302±0.00 0.863±0.00 0.388±0.14
ENST00000462275 N/A N/A N/A N/A 0.067±0.00
ENST00000469630 0.555±0.00 0.792±0.21 N/A N/A 0.252±0.24
ENST00000474763 N/A N/A N/A N/A 0.308±0.11
ENST00000476637 N/A N/A N/A 0.326±0.00 0.453±0.00
ENST00000481440 1.149±0.32 1.759±0.36 N/A N/A 0.495±0.27
ENST00000492560 N/A N/A N/A N/A 0.566±0.28
ENST00000493340 N/A N/A N/A 0.499±0.00 0.228±0.01
ENST00000494876 N/A N/A N/A N/A 0.963±0.49

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00030C CIL_00030C_0001 CGP
CIL_00023M CIL_00023M_0002 CGP
CIL_000309 CIL_000309_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004796 IEA thromboxane-A synthase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006690 TAS icosanoid metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0016021 IEA integral component of membrane
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019369 TAS arachidonic acid metabolic process
GO:0019371 TAS cyclooxygenase pathway
GO:0020037 IEA heme binding
GO:0030644 IEA cellular chloride ion homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0045907 IEA positive regulation of vasoconstriction
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002249 tbxas1 protein_coding Danio_rerio
ENSMUSG00000029925 Tbxas1 protein_coding Mus_musculus

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