ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polymerase (DNA directed), delta 1, catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000062822 POLD1 9606 + 19:50384204-50418018 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000440232 POLD1-002 50384339-50418014 protein_coding
  ENST00000593407 POLD1-008 50413503-50417063 protein_coding
  ENST00000593887 POLD1-012 50384373-50399484 protein_coding
  ENST00000593981 POLD1-011 50413866-50417923 protein_coding
  ENST00000595904 POLD1-004 50398852-50417947 protein_coding
  ENST00000596221 POLD1-006 50416953-50418010 retained_intron
  ENST00000596425 POLD1-009 50407084-50413501 protein_coding
  ENST00000596648 POLD1-010 50415509-50417091 retained_intron
  ENST00000597963 POLD1-007 50416313-50418016 retained_intron
  ENST00000599857 POLD1-001 50384351-50418014 protein_coding
  ENST00000600746 POLD1-005 50384367-50402665 retained_intron
  ENST00000600859 POLD1-003 50384204-50418012 nonsense_mediated_decay
  ENST00000601098 POLD1-013 50384342-50402142 protein_coding
  ENST00000613923 POLD1-201 50384323-50418018 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000440232ENST00000593407ENST00000593981ENST00000595904ENST00000596221ENST00000597963ENST00000599857ENST00000600746ENST00000600859ENST00000613923
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000440232 5.967±0.00 11.838±2.67 N/A 11.634±0.00 10.529±8.06
ENST00000593407 20.414±0.00 N/A N/A N/A N/A
ENST00000593981 36.297±10.37 N/A 11.757±0.00 N/A N/A
ENST00000595904 4.308±0.00 N/A N/A N/A 1.115±0.39
ENST00000596221 61.050±0.00 N/A 24.272±0.00 N/A N/A
ENST00000597963 24.978±0.00 N/A 9.527±0.00 N/A N/A
ENST00000599857 N/A 4.308±0.94 2.222±0.00 N/A 1.728±1.01
ENST00000600746 N/A N/A N/A N/A 6.481±0.00
ENST00000600859 N/A N/A N/A N/A 3.113±0.00
ENST00000613923 N/A 2.180±0.00 N/A N/A 2.832±0.80

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000109 IDA nucleotide-excision repair complex
GO:0000166 IEA nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0000731 IMP DNA synthesis involved in DNA repair
GO:0003676 IEA nucleic acid binding
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IMP:IEA DNA-directed DNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006260 IMP DNA replication
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006284 TAS base-excision repair
GO:0006287 IDA base-excision repair, gap-filling
GO:0006289 TAS nucleotide-excision repair
GO:0006297 IMP nucleotide-excision repair, DNA gap filling
GO:0007346 IBA regulation of mitotic cell cycle
GO:0008408 IBA 3'-5' exonuclease activity
GO:0009411 TAS response to UV
GO:0016020 IDA membrane
GO:0016235 IDA aggresome
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0043137 IBA DNA replication, removal of RNA primer
GO:0043625 IBA delta DNA polymerase complex
GO:0044281 TAS small molecule metabolic process
GO:0045004 IBA DNA replication proofreading
GO:0046872 IEA metal ion binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055089 IMP fatty acid homeostasis
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027689 pold1 protein_coding Danio_rerio
ENSMUSG00000038644 Pold1 protein_coding Mus_musculus

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