ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: transducin-like enhancer of split 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065717 TLE2 9606 - 19:2997638-3047635 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262953 TLE2-004 2997638-3029167 protein_coding
  ENST00000426948 TLE2-201 2997639-3045788 protein_coding
  ENST00000443826 TLE2-002 2997682-3029614 protein_coding
  ENST00000455444 TLE2-202 2997639-3029131 protein_coding
  ENST00000586422 TLE2-021 2997647-3028356 protein_coding
  ENST00000586492 TLE2-020 3005839-3008876 processed_transcript
  ENST00000587137 TLE2-015 3014597-3029043 protein_coding
  ENST00000587217 TLE2-013 3013747-3020589 processed_transcript
  ENST00000587672 TLE2-018 3009572-3019480 retained_intron
  ENST00000587770 TLE2-009 3019431-3025616 retained_intron
  ENST00000587893 TLE2-012 3019702-3025375 retained_intron
  ENST00000589205 TLE2-019 3009661-3019372 processed_transcript
  ENST00000589291 TLE2-014 3015715-3020227 processed_transcript
  ENST00000589364 TLE2-017 3005438-3025027 protein_coding
  ENST00000590101 TLE2-003 3014571-3028919 retained_intron
  ENST00000590183 TLE2-011 3014602-3025647 processed_transcript
  ENST00000590536 TLE2-006 2997848-3029013 protein_coding
  ENST00000591457 TLE2-016 3013791-3045730 protein_coding
  ENST00000591529 TLE2-001 2997646-3047635 protein_coding
  ENST00000591720 TLE2-007 3019553-3029622 retained_intron
  ENST00000592305 TLE2-010 3019500-3029034 retained_intron
  ENST00000592584 TLE2-008 3019301-3029613 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000262953ENST00000426948ENST00000443826ENST00000455444ENST00000587137ENST00000589205ENST00000590536
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000262953 1.755±0.71 N/A 2.156±0.00 7.887±9.59
ENST00000426948 N/A N/A N/A 3.187±4.20
ENST00000443826 N/A N/A N/A 2.996±0.91
ENST00000455444 6.705±2.57 14.524±0.00 3.675±0.00 2.406±1.58
ENST00000587137 6.219±0.00 N/A N/A N/A
ENST00000589205 N/A N/A N/A 31.042±0.00
ENST00000590536 0.686±0.14 N/A N/A 3.787±2.55

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 TAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0009887 TAS organ morphogenesis
GO:0016055 IEA Wnt signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000034771 Tle2 protein_coding Mus_musculus

Loading